Shin-Huei Fu

TL;DR: It appears that the fatty acid moiety of PB, rather than its aromatic ring, is critical for its activity in myeloid leukemic cells, which provides a potential mechanistic basis for the increased potency of PB over PA previously demonstrated in primary leukedmic samples, and support the further clinical development of PB in the treatment of hematologic malignancies.

TL;DR: The emerging roles of Blimp-1 in the complex regulation of gene networks that regulate the destiny and effector function of T cells and provide a Blimp-1-dominated transcriptional framework for T lymphocyte homeostasis are discussed.

TL;DR: Intraperitoneal transplantation of the microencapsulated islets into streptozotocin-induced diabetic mice could maintain normal blood glucose levels in test animals for up to 200 d without immunosuppression.

TL;DR: Experimental results and observations by SEM suggested that loofa sponge is a suitable scaffold for high‐density culture of human hepatocyte cell line and the immobilized cells could express high levels of liver‐specific functions.

TL;DR: It is demonstrated that glucosamine impedes Th1, Th2, and iTreg cells but promotes Th17 differentiation through down-regulating N-linked glycosylation of CD25 and subsequently inhibiting its downstream Stat5 signaling in a dose-dependent manner.