S
Shin-ichi Tokushige
Researcher at University of Tokyo
Publications - 33
Citations - 209
Shin-ichi Tokushige is an academic researcher from University of Tokyo. The author has contributed to research in topics: Saccade & Parkinsonism. The author has an hindex of 7, co-authored 32 publications receiving 138 citations. Previous affiliations of Shin-ichi Tokushige include Kyorin University.
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Journal ArticleDOI
Three-Year Follow-Up of High-Dose Ubiquinol Supplementation in a Case of Familial Multiple System Atrophy with Compound Heterozygous COQ2 Mutations.
Jun Mitsui,Ken Koguchi,Toshimitsu Momose,Miwako Takahashi,Takashi Matsukawa,Tsutomu Yasuda,Shin-ichi Tokushige,Hiroyuki Ishiura,Jun Goto,Shigeaki Nakazaki,Tomoyoshi Kondo,Hidefumi Ito,Yorihiro Yamamoto,Shoji Tsuji +13 more
TL;DR: A 3-year follow-up of high-dose ubiquinol supplementation in a case of familial multiple system atrophy with compound heterozygous nonsense (R387X) and missense (V393A) mutations in COQ2 suggests the therapeutic potential of Ubiquinol for patients with MSA withCOQ2 mutations.
Journal ArticleDOI
The intensity of continuous theta burst stimulation, but not the waveform used to elicit motor evoked potentials, influences its outcome in the human motor cortex.
Takuya Sasaki,Satoshi Kodama,Naohiko Togashi,Yuichiro Shirota,Yusuke Sugiyama,Shin-ichi Tokushige,Satomi Inomata-Terada,Yasuo Terao,Yoshikazu Ugawa,Masashi Hamada +9 more
TL;DR: Current directions in MEP measurement had no influence on the responses to cTBS, and lowering stimulus intensity induced the expected after-effects of cTbs in some subjects.
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Isolated pyramidal tract impairment in the central nervous system of adult-onset Krabbe disease with novel mutations in the GALC gene.
Shin-ichi Tokushige,Tomohiro Sonoo,Risa Maekawa,Yuichiro Shirota,Ritsuko Hanajima,Yasuo Terao,Hideyuki Matsumoto,Mohammad Arif Hossain,Norio Sakai,Yasushi Shiio +9 more
TL;DR: The findings show that adult-onset Krabbe disease is characterized by isolated pyramidal tract impairment in the central nervous system, both neurophysiologically and radiologically.
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Rectal Ulcer in a Patient with VZV Sacral Meningoradiculitis (Elsberg Syndrome)
Hideyuki Matsumoto,Takahiro Shimizu,Shin-ichi Tokushige,Hideo Mizuno,Yukifusa Igeta,Hideji Hashida +5 more
TL;DR: A 55-year-old woman with varicella-zoster virus (VZV) sacral meningoradiculitis (Elsberg syndrome) who presented with herpes zoster in the left S2 dermatome area, urinary retention, and constipation suddenly showed massive hematochezia and hemorrhagic shock because of a rectal ulcer.
Journal ArticleDOI
Partial duplication of DHH causes minifascicular neuropathy: A novel mutation detection of DHH.
Naoko Saito Sato,Risa Maekawa,Hiroyuki Ishiura,Jun Mitsui,Hiroya Naruse,Shin-ichi Tokushige,Kazuma Sugie,Genshu Tate,Jun Shimizu,Jun Goto,Jun Goto,Shoji Tsuji,Yasushi Shiio +12 more
TL;DR: An identical novel rearrangement mutation of DHH is identified in two consanguineous families with MN, confirming mutations in DHH cause MN with 46XY GD, and further support that DHH has important roles in perineural formation and male gonadal differentiation.