S
Shin-ichiro Fujiwara
Researcher at Jichi Medical University
Publications - 121
Citations - 5737
Shin-ichiro Fujiwara is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 14, co-authored 107 publications receiving 5134 citations.
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Journal ArticleDOI
Associations between the peripheral blood Wilms tumor gene 1 level and both bone marrow blast cells and the prognosis in patients with myelodysplastic syndrome.
Kiyomi Mashima,Takashi Ikeda,Yumiko Toda,Shoko Ito,Kento Umino,Daisuke Minakata,Hirofumi Nakano,Kaoru Morita,Ryoko Yamasaki,Yasufumi Kawasaki,Miyuki Sugimoto,Masahiro Ashizawa,Chihiro Yamamoto,Shin-ichiro Fujiwara,Kaoru Hatano,Kazuya Sato,Iekuni Oh,Ken Ohmine,Kazuo Muroi,Yoshinobu Kanda +19 more
TL;DR: Among the allogeneic transplant recipients, the presence of two consecutive WT1 levels ≥100 copies/μg RNA with a median interval of one month was associated with a 77.8% relapse rate at nine months from the first detection of a high WT1 level.
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Cytogenetic risk stratification may predict allogeneic hematopoietic stem cell transplantation outcomes for chronic myelomonocytic leukemia
Kenji Motohashi,Shin Fujisawa,Noriko Doki,Takeshi Kobayashi,Takehiko Mori,Kensuke Usuki,Masatsugu Tanaka,Shin-ichiro Fujiwara,Shinichi Kako,Yasuyuki Aoyama,Masahiro Onoda,Shingo Yano,Moritaka Gotoh,Heiwa Kanamori,Satoshi Takahashi,Shinichiro Okamoto +15 more
TL;DR: The data suggest that the CMML-specific cytogenetic risk stratification at transplant may be useful for identifying patients with CMML who may benefit from HSCT, however, further studies are warranted to confirm this observation.
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Combination of tipifarnib and rapamycin synergistically inhibits the growth of leukemia cells and overcomes resistance to tipifarnib via alteration of cellular signaling pathways.
TL;DR: A combination of a farnesyltransferase inhibitor, tipifarnib, and an mTOR inhibitor, rapamycin, synergistically inhibited the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage.
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Use of cryoprotectant-depleted allogeneic peripheral blood stem cells for transplantation
Yuji Hirata,Koji Kishino,Fumiko Onozaki,Yoko Nakaki,Shin-ichiro Fujiwara,Chizuru Yamamoto,Kazuya Sato,Tomohiro Matsuyama,Katsutoshi Ozaki,Masaki Mori,Keiya Ozawa,Kazuo Muroi +11 more
TL;DR: The results suggest the removal of DMSO from thawed PBSCs to be safe and useful for transplantation.
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CD56 expression in normal immature granulocytes after allogeneic hematopoietic stem cell transplantation.
Kazuo Muroi,Shin-ichiro Fujiwara,Raine Tatara,Miyuki Sugimoto,Chihiro Yamamoto,Eisuke Uehara,Akiko Meguro,Kaoru Hatano,Kiyoshi Okazuka,Iekuni Oh,Ken Ohmine,Takahiro Suzuki,Masaki Mori,Tadashi Nagai,Keiya Ozawa +14 more
TL;DR: Results indicate that CD56 can be expressed in normal immaturegranulocytes at a variety of expression levels in regenerative bone marrow, and attention should be paid when evaluating aberrant antigen expression of CD56 in granulocytes.