K
Kaoru Hatano
Researcher at Jichi Medical University
Publications - 60
Citations - 427
Kaoru Hatano is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 10, co-authored 50 publications receiving 284 citations.
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Journal ArticleDOI
Rituximab plus 70% cyclophosphamide, doxorubicin, vincristine and prednisone for Japanese patients with diffuse large B-cell lymphoma aged 70 years and older.
Akiko Meguro,Katsutoshi Ozaki,Kazuya Sato,Iekuni Oh,Shin-ichiro Fujiwara,Rie Hosonuma,Miyuki Sasazaki,Yuji Kikuchi,Yuji Hirata,Chihiro Yamamoto,Mitsuyo Uesawa,Hiroyuki Kobayashi,Haruko Matsu,Hiroshi Okabe,Eisuke Uehara,Akinori Nishikawa,Raine Tatara,Kaoru Hatano,Chizuru Yamamoto,Tomohiro Matsuyama,Masaki Toshima,Masuzu Ueda,Ken Ohmine,Takahiro Suzuki,Masaki Mori,Tadashi Nagai,Kazuo Muroi,Keiya Ozawa +27 more
TL;DR: Three-year PFS with R-70%CHOP for patients aged 70 years and older was not significantly worse than that with full-dose R-CHop for younger patients, suggesting that R- 70% CHOP might be a reasonable choice for patients with DLBCL aged 70 year and older, especially for those with comorbidities.
Journal ArticleDOI
Analysis of the cost-effectiveness of treatment strategies for CML with incorporation of treatment discontinuation.
Chihiro Yamamoto,Hirotomo Nakashima,Takashi Ikeda,Shin-Ichiro Kawaguchi,Yumiko Toda,Shoko Ito,Kiyomi Mashima,Takashi Nagayama,Kento Umino,Daisuke Minakata,Hirofumi Nakano,Kaoru Morita,Ryoko Yamasaki,Miyuki Sugimoto,Yuko Ishihara,Masahiro Ashizawa,Kaoru Hatano,Kazuya Sato,Iekuni Oh,Shin-ichiro Fujiwara,Masuzu Ueda,Ken Ohmine,Kazuo Muroi,Yoshinobu Kanda +23 more
TL;DR: Imatinib first was shown to be the most cost-effective approach even with the incorporation of stop TKI, and the results were robust to univariate and multivariate sensitivity analyses.
Journal ArticleDOI
Clinical outcomes of myeloid/lymphoid neoplasms with fibroblast growth factor receptor-1 (FGFR1) rearrangement.
Kento Umino,Shin-ichiro Fujiwara,Takashi Ikeda,Yumiko Toda,Shoko Ito,Kiyomi Mashima,Daisuke Minakata,Hirofumi Nakano,Ryoko Yamasaki,Yasufumi Kawasaki,Miyuki Sugimoto,Chihiro Yamamoto,Masahiro Ashizawa,Kaoru Hatano,Kazuya Sato,Iekuni Oh,Ken Ohmine,Kazuo Muroi,Yoshinobu Kanda +18 more
TL;DR: Myeloid/lymphoid neoplasms with fibroblast growth factor receptor-1 (FGFR1) rearrangement are hematopoietic stem cell disorders with a poor prognosis, but no established standard therapy.
Journal ArticleDOI
Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies
Daisuke Minakata,Shin-ichiro Fujiwara,Takashi Ikeda,Shin-Ichiro Kawaguchi,Yumiko Toda,Shoko Ito,Shin-Ichi Ochi,Takashi Nagayama,Kiyomi Mashima,Kento Umino,Hirofumi Nakano,Ryoko Yamasaki,Kaoru Morita,Yasufumi Kawasaki,Miyuki Sugimoto,Chihiro Yamamoto,Masahiro Ashizawa,Kaoru Hatano,Kazuya Sato,Iekuni Oh,Ken Ohmine,Kazuo Muroi,Tsukasa Ohmori,Yoshinobu Kanda +23 more
TL;DR: Resolution of DIC was correlated with improvement of background hematological malignancies, and no significant differences were observed between the two SPIs.
Journal ArticleDOI
Comprehensive Analysis of the Activation and Proliferation Kinetics and Effector Functions of Human Lymphocytes, and Antigen Presentation Capacity of Antigen-Presenting Cells in Xenogeneic Graft-Versus-Host Disease.
Yasufumi Kawasaki,Kazuya Sato,Hiroko Hayakawa,Norihito Takayama,Hirofumi Nakano,Ryoji Ito,Kiyomi Mashima,Iekuni Oh,Daisuke Minakata,Ryoko Yamasaki,Kaoru Morita,Masahiro Ashizawa,Chihiro Yamamoto,Kaoru Hatano,Shin-ichiro Fujiwara,Ken Ohmine,Kazuo Muroi,Yoshinobu Kanda +17 more
TL;DR: It is demonstrated that host hematopoietic, but not nonhematopoetic, APCs play a critical role in the development of CD4+ T cell-mediated GVHD, and this findings provide a better understanding of the immunobiology of humanized mice and support theDevelopment of novel options for the prevention and treatment for GV HD.