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Shinya Kaname
Researcher at Kyorin University
Publications - 99
Citations - 2184
Shinya Kaname is an academic researcher from Kyorin University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 22, co-authored 80 publications receiving 1783 citations. Previous affiliations of Shinya Kaname include Memorial Hospital of South Bend & University of Tokyo.
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Journal ArticleDOI
Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial
Kenjiro Kimura,Tatsuo Hosoya,Shunya Uchida,Masaaki Inaba,Hirofumi Makino,Shoichi Maruyama,Sadayoshi Ito,Tetsuya Yamamoto,Yasuhiko Tomino,Iwao Ohno,Yugo Shibagaki,Satoshi Iimuro,Naohiko Imai,Masanari Kuwabara,Hiroshi Hayakawa,Hiroshi Ohtsu,Yasuo Ohashi,Seiichi Matsuo,Hisashi Yamanaka,Tadao Akizawa,Tamio Teramoto,Hiroshi Kasanuki,Kenichi Yoshimura,Hiroshi Sato,Satoshi Horikoshi,Syoichi Maruyama,Masahiko Inaba,Yuji Moriwaki,Haruhito Uchida,Nagayuki Kaneshiro,Hidekazu Moriya,Yasuhiro Komatsu,Shinya Kaname,Kazunari Hanaoka,Makoto Ogura,Masato Ikeda,Kenji Kasai,Akira Sugiura,Kazushi Takahashi,Kenichiro Kojima,Kosaku Nitta,Hirofumi Tamai,Hiroshi Nagaya,Senji Okuno,Ryusuke Kakiya,Hiroya Takeoka,Kyouji Hirata,Kenichiro Asano,Yasuo Fukaya,Yasushi Iwaida,Yasuo Tsuneda,Shigeaki Nishimura,Takeyuki Hiramatsu,Yoshitaka Isaka,Takafumi Ito,Yukio Yuzawa,Kunihiro Yamagata,Tadashi Sofue,Yoshimi Jinguji,Keita Hirano,Kazuhiro Matsuyama,Teruhiko Mizumoto,Yuko Shibuya,Masahiro Sugawara,Moritoshi Kadomura,Yasuaki Teshima,Hiroshi Ohtani,Hiroki Kamata,Susumu Okawara,Masaki Fukushima,Katsumi Takemura,Eriko Kinugasa,Masami Kogure,Yoichi Ehara +73 more
TL;DR: Compared to placebo, febuxostat did not mitigate the decline in kidney function among patients with stage 3 CKD and asymptomatic hyperuricemia andSubgroup analysis demonstrated a significant benefit from febUXostat in patients without proteinuria and for whom serum creatinine concentration was lower than the median.
Journal ArticleDOI
Regression of parathyroid hyperplasia by calcitriol-pulse therapy in patients on long-term dialysis.
Masafumi Fukagawa,Okazaki R,Takano K,Shinya Kaname,Etsuro Ogata,Masafumi Kitaoka,Harada S,N. Sekine,Takumi Matsumoto,Kiyoshi Kurokawa +9 more
Journal ArticleDOI
Regulation of parathyroid hormone synthesis in chronic renal failure in rats
TL;DR: The data suggest that secondary hyperparathyroidism in early chronic renal failure may be due in part to the resistance of parathyroid cells to the physiological concentration of 1,25(OH)2D in circulation on PTH synthesis and that 22-oxa-1,25
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Redox-sensitive regulation of lox-1 gene expression in vascular endothelium.
TL;DR: Results indicated redox-sensitive upregulation of LOX-1 mRNA in both in vitro and in vivo systems, suggesting its potential role in atherosclerosis.
Journal ArticleDOI
Autocrine secretion of transforming growth factor-β in cultured rat mesangial cells
TL;DR: Mesangial cells produce and secrete substantial amounts of TGF-beta but mostly in latent forms, and the secreted T GF-beta may regulate mesangial cell growth and differentiation.