S
Shoichi Harima
Researcher at Kyoto Pharmaceutical University
Publications - 14
Citations - 780
Shoichi Harima is an academic researcher from Kyoto Pharmaceutical University. The author has contributed to research in topics: Chrysanthemum indicum & Rhaponticin. The author has an hindex of 7, co-authored 14 publications receiving 753 citations.
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Journal ArticleDOI
Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides.
Hisashi Matsuda,Toshio Morikawa,Iwao Toguchida,Ji-Young Park,Shoichi Harima,Masayuki Yoshikawa +5 more
TL;DR: The methanolic extracts from five kinds of rhubarb were found to show scavenging activity for DPPH radical and .O2- and several stilbenes with both the 3-hydroxyl and 4'-methoxyl groups inhibited xanthine oxidase.
Journal ArticleDOI
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.
Hisashi Matsuda,Tadashi Kageura,Toshio Morikawa,Iwao Toguchida,Shoichi Harima,Masayuki Yoshikawa +5 more
TL;DR: Two new anthraquinone glucosides and two stilbene glucoside gallates showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, and the active stilbenes inhibited iNOS induction.
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Medicinal flowers. VI. Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.: their inhibitory activities for rat lens aldose reductase.
TL;DR: Two new flavanone glycosides were found to show inhibitory activity for rat lens aldose reductase and a new phenylbutanoid glycoside, (2S, 3S)-1-phenyl-2,3-butanediol 3-O-beta-D-glucopyranoside, were isolated from the flowers of Chrysanthemum indicum L. cultivated in China together with eight flavonoids.
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Medicinal flowers. II. Inhibitors of nitric oxide production and absolute stereostructures of five new germacrane-type sesquiterpenes, kikkanols D, D monoacetate, E, F, and F monoacetate from the flowers of Chrysanthemum indicum L.
TL;DR: The methanolic extract and ethyl acetate-soluble portion from the flowers of Chrysanthemum indicum L. were found to show inhibitory activity against nitric oxide (NO) production in lipopolysaccharide-activated macrophages.
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Medicinal flowers. I. Aldose reductase inhibitors and three new eudesmane-type sesquiterpenes, kikkanols A, B, and C, from the flowers of Chrysanthemum indicum L.
Masayuki Yoshikawa,Toshio Morikawa,Toshiyuki Murakami,Iwao Toguchida,Shoichi Harima,Hisashi Matsuda +5 more
TL;DR: The methanolic extract from the flowers of Chrysanthemum indicum L was found to show inhibitory activity against rat lens aldose reductase and three new eudesmane-type sesquiterpenes, kikkanols A, B, and C were elucidated on the basis of chemical and physicochemical evidence.