Shou-Guo Wang

TL;DR: This analysis comprehensively review all asymmetric transition-metal-catalyzed methodologies that are believed to proceed via an inner-sphere-type mechanism, with an emphasis on the nature of stereochemistry generation.

TL;DR: Chiral phosphoric acid worked together with Hoveyda-Grubbs II catalyst enabling highly efficient synthesis of enantioenriched tetrahydro-β-carbolines through a ring-closing metathesis/isomerization/Pictet-Spengler cascade reaction via sequential catalysis.

TL;DR: A highly efficient catalytic asymmetric dearomatization of naphthols by means of an electrophilic amination reaction catalyzed by chiral phosphoric acid is presented, providing a facile access to functionalized β-naphthalenone compounds with a chiral quaternary carbon center in excellent yields and enantioselectivity.

TL;DR: An intermolecular asymmetric dearomatization reaction of β-naphthols with nitroethylene through a chiral-thiourea-catalyzed Michael reaction is described and enantioenriched functionalized β- naphthalenones with an all-carbon quaternary stereogenic center could be easily constructed from simple naphthol derivatives in good yields and excellent enantioselectivity.

TL;DR: A highly enantioselective chlorinative dearomatization of 1-naphthol and 2- naphthols was realized for the first time, providing chiral naphthalenones with a Cl-containing all-substituted stereocenter in excellent yields and enantiOSElectivity.