Shreya Sharma

TL;DR: It is shown that rVAR2 efficiently captures CTCs from hepatic, lung, pancreatic, and prostate carcinoma patients with minimal contamination of peripheral blood mononuclear cells and targets a larger and more diverse population of C TCs compared to anti-EpCAM strategies.

TL;DR: This work summarizes how extracellular and cellular elements of the pancreatic tumor microenvironment and their interactions have been studied in 3D cell cultures and assess the benefits of therapies interfering with the tumor micro environment.

TL;DR: The overexpression of SIRT2 and SIRT7 proteins in cervical cancer is reported and probable application of sirtuin inhibitors as therapeutic targets are suggested.

TL;DR: It is demonstrated that CD4+ CD25+hi Tregs from HBVHCC patients have decreased expression of PD1, resulting in higher IL-10 and TGF-β secretion, which confers increased anti-tumor suppressive response than in non-HBV-HCC.

TL;DR: HGF, IL 6, TNF‐α, and TPO are involved in the early phase of liver regeneration, whereas TGF‐β1 and IFN are involvedIn conclusion, liver regeneration was observed to be higher in donors with low RLVBWR.