S
Shruti M. Paranjape
Researcher at Johns Hopkins University
Publications - 20
Citations - 520
Shruti M. Paranjape is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Cystic fibrosis & Precision medicine. The author has an hindex of 12, co-authored 18 publications receiving 456 citations. Previous affiliations of Shruti M. Paranjape include Boston Children's Hospital & Kennedy Krieger Institute.
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Journal ArticleDOI
Activity of the De Novo Engineered Antimicrobial Peptide WLBU2 against Pseudomonas aeruginosa in Human Serum and Whole Blood: Implications for Systemic Applications
Berthony Deslouches,Kazi Islam,Jodi K. Craigo,Shruti M. Paranjape,Ronald C. Montelaro,Timothy A. Mietzner +5 more
TL;DR: A potential application of WLBU2 in the treatment of bacterial sepsis is established because of its ability to specifically eliminate P. aeruginosa in coculture with human monocytes or skin fibroblasts without detectable adverse effects to the host cells.
Journal ArticleDOI
Atypical cystic fibrosis and CFTR-related diseases
TL;DR: Diagnostic methods and phenotypic characteristics of classic and atypical CF, as well as CFTR-related diseases, conditions in which mutated CFTR may contribute to the pathogenesis but do not strictly fit established diagnostic criteria are described.
Journal ArticleDOI
Exercise improves lung function and habitual activity in children with cystic fibrosis
Shruti M. Paranjape,Laura A. Barnes,Kathryn A. Carson,Karen von Berg,H. Loosen,Peter J. Mogayzel +5 more
TL;DR: Increases in exercise capacity over a two-month period resulted in significantly improved lung function and self-reported habitual activity.
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American Society of Transplantation Executive Summary on Pediatric Lung Transplantation
Albert Faro,George B. Mallory,Gary A. Visner,Okan Elidemir,Peter J. Mogayzel,Lara Danziger-Isakov,Marian G. Michaels,Stuart C. Sweet,Peter H. Michelson,Shruti M. Paranjape,Carol Conrad,D. A. Waltz +11 more
TL;DR: This consensus statement reviews the experience in the field of pediatric lung transplantation and highlights areas that deserve further investigation.
Journal ArticleDOI
Baseline Ultrasound and Clinical Correlates in Children with Cystic Fibrosis
Daniel H. Leung,Wen Ye,Jean P. Molleston,Alexander Weymann,Simon C. Ling,Shruti M. Paranjape,Rene Romero,Sara J ane Schwarzenberg,Joseph J. Palermo,Estella M. Alonso,Karen F. Murray,Bruce C. Marshall,Averell H. Sherker,Marilyn J. Siegel,Rajesh Krishnamurthy,Roger K. Harned,Boaz Karmazyn,John C. Magee,Michael R. Narkewicz +18 more
TL;DR: Abnormal ultrasound is associated with CF-related diabetes, and early P aeruginosa is associatedWith normal ultrasound, and Prospective assessment of these risk factors may identify potential interventional targets.