Shuangsuo Dang

TL;DR: It is demonstrated that SSd could attenuate the area and extent of necrosis and reduce the scores of liver fibrosis in rats induced by CCl(4) injections in combination with alcohol and high fat, low protein feeding and its relationship with the expression of nuclear factor-kappaB, tumor necrosis factor-alpha and interleukins-6.

TL;DR: Emodin and APS have a weak but persistent inhibitory effect on HBV replication in vivo, which may function as a supplementary modality in the treatment of hepatitis B infection.

TL;DR: Overall, SVR was lower in HCC compared to non-HCC patients, especially in those with active HCC though heterogeneity was high, and Continued efforts are needed to aggressively screen, diagnose and treat HCC to ensure higher CHC cure rates.

TL;DR: Direct‐acting antiviral regimens have shown high efficacy and tolerability for patients with HCV genotype 1/1b (GT1/1B) in clinical trials, but robust real‐world evidence of interferon (IFN)‐free DAA treatment for HCV GT1‐infected patients in Asia is still lacking.

TL;DR: This study characterizes Th-17 and Treg cells in the blood of HBV-associated acute-on-chronic liver failure (ACLF) patients, and aids the understanding of how the two subsets of CD4(+) T cells affect each other and contribute to survival.