Shuo-Qing Zhang

TL;DR: The Pd(II)-catalyzed alkoxylation of unactivated C(sp3)–H and C( sp2)-H bonds using a new bidentate directing group has been developed and is readily available and removable.

TL;DR: A palladium-catalyzed alkylation of primary and secondary C(sp3)–H bonds with alkyl iodides and/or bromides for the synthesis of optically active unnatural α-amino acids (α-AAs) is described, providing an efficient new strategy for the synthesisation of various unnatural α -amino acid derivatives.

TL;DR: This method allows the site- and diastereoselective fluorination of β-methylene C(sp(3))-H bonds of α-amino acid derivatives and is consistent with direct C-F reductive elimination from a high-valent intermediate.

TL;DR: The mechanisms and chemo- and regioselectivities of Ru(II)-catalyzed decarboxylative C-H alkenylation of aryl carboxylic acids with alkynes were investigated with density functional theory (DFT) calculations and the polarity of solvent is found to control the chemoselectivity.

TL;DR: In this article, the trifluoromethyl functional groups (−CF3) in the molecule structure of a SEI can significantly tune the orbital energies and the HOMO-LUMO gap due to the strong electron-withdrawing property of −CF3 functional groups.