S
Si Ming Man
Researcher at Australian National University
Publications - 83
Citations - 9762
Si Ming Man is an academic researcher from Australian National University. The author has contributed to research in topics: Inflammasome & Pyroptosis. The author has an hindex of 38, co-authored 68 publications receiving 6813 citations. Previous affiliations of Si Ming Man include St. Jude Children's Research Hospital & University of Cambridge.
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Global Epidemiology of Campylobacter Infection
TL;DR: Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come.
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Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.
TL;DR: The central role of inflammatory caspases and pyroptosis in mediating immunity to infection and clearance of pathogens is described.
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Regulation of inflammasome activation
TL;DR: Genetic studies indicate that mutations in NLRP1, NLRP3, NLRC4, and AIM2 are linked with the development of auto‐inflammatory diseases, enterocolitis, and cancer and transform the understanding of the basic biology and clinical relevance of inflammasomes.
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Converging roles of caspases in inflammasome activation, cell death and innate immunity.
TL;DR: The expanding and interconnected roles of caspases that highlight new aspects of this family of cysteine proteases in innate immunity are discussed.
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ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
Teneema Kuriakose,Si Ming Man,R. K. Subbarao Malireddi,Rajendra Karki,Sannula Kesavardhana,David E. Place,Geoffrey Neale,Peter Vogel,Thirumala-Devi Kanneganti +8 more
TL;DR: Findings indicate that ZBP1 is an innate immune sensor of IAV and highlight its importance in the pathogenesis of I AV infection.