S
Siarhei A. Dabravolski
Researcher at Central European Institute of Technology
Publications - 44
Citations - 556
Siarhei A. Dabravolski is an academic researcher from Central European Institute of Technology. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 6, co-authored 23 publications receiving 218 citations. Previous affiliations of Siarhei A. Dabravolski include Palacký University, Olomouc.
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Journal ArticleDOI
The Role of Mitochondrial Abnormalities in Diabetic Cardiomyopathy
Siarhei A. Dabravolski,Nikolay K. Sadykhov,Andrey G. Kartuesov,E. Borisov,Vasily N. Sukhorukov,Alexander N. Orekhov +5 more
TL;DR: This review focuses on the role of mitochondrial dynamics, biogenesis and mitophagy, Ca2+ metabolism and bioenergetics in the DCM development and progression and proposes strategies to slow down the progression of the disease.
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The Role of Mitochondria Dysfunction in Inflammatory Bowel Diseases and Colorectal Cancer.
TL;DR: In this article, the role of mitochondria mutations and dysfunctions in IBD and colorectal cancer (CRC) was discussed, and the main mitochondria-related molecular pathways involved in the transition from IBD to CRC transition were discussed.
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Role of the mtDNA Mutations and Mitophagy in Inflammaging
Siarhei A. Dabravolski,Nikita G. Nikiforov,A.D. Zhuravlev,N. Alexander Orekhov,Andrey V. Grechko,Alexander N. Orekhov +5 more
TL;DR: The role of mitochondrial metabolism, mitochondria generated ROS, mitochondrial dynamics and mitophagy in normal ageing and pathological conditions, such as inflammation, are focused on.
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Heat Shock Protein 90 as Therapeutic Target for CVDs and Heart Ageing
Siarhei A. Dabravolski,Vasily N. Sukhorukov,V A Kalmykov,N. Alexander Orekhov,Andrey V. Grechko,Alexander N. Orekhov +5 more
TL;DR: The recently investigated role of H SP90 proteins in cardioprotection, atherosclerosis, CVDs development and the involvements of HSP90 clients in the activation of different molecular pathways and signalling mechanisms, related to heart ageing are discussed.
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Antibody-mediated modulation of cytokinins in tobacco: organ-specific changes in cytokinin homeostasis.
Zuzana Gelová,Zuzana Gelová,Petra ten Hoopen,Ondřej Novák,Václav Motyka,Markéta Pernisová,Markéta Pernisová,Siarhei A. Dabravolski,Vojtěch Didi,Isolde Tillack,Jana Oklešťková,Miroslav Strnad,Bettina Hause,Danka Haruštiaková,Udo Conrad,Lubomír Janda,Lubomír Janda,Jan Hejátko,Jan Hejátko +18 more
TL;DR: The roots are suggested as the main site of cytokinin biosynthesis in tobacco seedlings, and cytokinIn levels in the shoot seem to depend largely on long-range transport of cytkinin ribosides from the root and their subsequent metabolic activation.