Siddhartha Kar

TL;DR: A codon 249 mutation of the p53 gene identifies an endemic form of HCC strongly associated with dietary aflatoxin intake, which is correlated with high risk of exposure to aflatoxins and the hepatitis B virus.

TL;DR: Current knowledge on cancer chemopreventive effects of a few highly promising dietary constituents, including garlic‐derived organosulfides, berry compounds, and cruciferous vegetable‐derived isothiocyanates is reviewed, and serves to illustrate complexity of the signal transduction mechanisms in cancerChemoprevention by these promising bioactive food components.

TL;DR: The results indicated that vitamin K-related quinoid compounds cause growth inhibition and both apoptotic and necrotic cell death and that the effects may be mediated by interaction at position 3 of their quinoids nuclei with cellular thiols.

TL;DR: Bartonella bacilliformis, which causes the human diseases Oroya fever and verruga peruana, binds to human erythrocytes in vitro and produces substantial and long-lasting deformations in ERYthrocyte membranes, including cone-shaped depressions, trenches, and deep invaginations.

TL;DR: Comparative data are presented on the potencies of JS-K and 41 other O(2)-arylated diazeniumdiolates as inhibitors of HL-60 human leukemia cell proliferation as well as in the NCI 51-cell-line screen for six of them to suggest that other features of its structure and metabolism besides NO release may contribute importantly to its activity.