S
Sidney M Bell
Researcher at Fred Hutchinson Cancer Research Center
Publications - 11
Citations - 2565
Sidney M Bell is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Cross-species transmission & Dengue virus. The author has an hindex of 7, co-authored 11 publications receiving 1425 citations. Previous affiliations of Sidney M Bell include University of Washington.
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Journal ArticleDOI
Nextstrain: real-time tracking of pathogen evolution.
James Hadfield,Colin Megill,Sidney M Bell,Sidney M Bell,John Huddleston,John Huddleston,Barney Potter,Charlton Callender,Pavel Sagulenko,Trevor Bedford,Richard A. Neher,Richard A. Neher,Richard A. Neher +12 more
TL;DR: Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and an interactive visualization platform that presents a real-time view into the evolution and spread of a range of viral pathogens of high public health importance.
Journal ArticleDOI
Identification of a Polymorphism in the N Gene of SARS-CoV-2 That Adversely Impacts Detection by Reverse Transcription-PCR.
Manu Vanaerschot,Sabrina A Mann,James T. Webber,Jack Kamm,Sidney M Bell,John Bell,Si Noon Hong,Minh Phuong Nguyen,Lienna Y. Chan,Karan D. Bhatt,Michelle Tan,Angela M. Detweiler,Alex Espinosa,Wesley Wu,Joshua Batson,David Dynerman,Debra A. Wadford,Andreas S. Puschnik,Norma Neff,Vida Ahyong,Steve Miller,Patrick Ayscue,Cristina M. Tato,Simon Paul,Amy Kistler,Joseph L. DeRisi,Emily D. Crawford +26 more
TL;DR: Since April 7, 2020, the COVID-19 diagnostic laboratory (CLIAHUB) has received samples from multiple counties in California - the RT-PCR protocol employs N-Gene and E-gene simplex assays.
Posted ContentDOI
cellxgene: a performant, scalable exploration platform for high dimensional sparse matrices
Colin Megill,Martin B,Weaver C,Sidney M Bell,Prins L,Badajoz S,McCandless B,Angela Oliveira Pisco,Kinsella M,Griffin F,Justin T. Kiggins,Haliburton G,Mani A,Weiden M,Dunitz M,Lombardo M,Huang T,Smith T,Chambers S,Jeremy Freeman,Cool J,Antony M. Carr +21 more
TL;DR: Cellxgene as mentioned in this paper is a web-based interface for exploring high-dimensional datasets along categorical, continuous and spatial dimensions, as well as feature annotation, with the ability to handle millions of observations.
Journal ArticleDOI
Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission.
Sidney M Bell,Trevor Bedford +1 more
TL;DR: 14 novel, well-supported, ancient cross-species transmission events are identified and lentiviral lineages vary widely in their ability to infect new host species: SIVcol (from colobus monkeys) is evolutionarily isolated, while SIVagms (from African green monkeys) frequently move between host subspecies.
Journal ArticleDOI
Dengue genetic divergence generates within-serotype antigenic variation, but serotypes dominate evolutionary dynamics.
TL;DR: A sequence-based model is constructed to directly map antigenic change to underlying genetic divergence, and identifies 49 specific substitutions and four colinear substitution clusters that robustly predict dengue antigenic relationships.