S
Siew Ping Han
Researcher at University of Queensland
Publications - 13
Citations - 979
Siew Ping Han is an academic researcher from University of Queensland. The author has contributed to research in topics: Cadherin & Adherens junction. The author has an hindex of 11, co-authored 13 publications receiving 862 citations.
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Journal ArticleDOI
Functional diversity of the hnRNPs: past, present and perspectives.
TL;DR: The current literature is reviewed to examine hnRNP diversity, and how this impacts upon approaches to the classification of RNA-binding proteins in general is discussed.
Journal ArticleDOI
A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens
Suzie Verma,Siew Ping Han,Magdalene Michael,Guillermo A. Gomez,Zhe Yang,Rohan D. Teasdale,Aparna Ratheesh,Eva M Kovacs,Radiya G. Ali,Alpha S. Yap +9 more
TL;DR: WAVE2–Arp2/3 is a major nucleator of actin assembly at the zonula adherens and likely acts in response to junctional Rac signaling and supports myosin II recruitment to, and tension generation at the junction.
Journal ArticleDOI
Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions
Magdalene Michael,Magdalene Michael,Joyce C.M. Meiring,Bipul R. Acharya,Daniel R. Matthews,Suzie Verma,Siew Ping Han,Michelle M. Hill,Robert G. Parton,Guillermo A. Gomez,Alpha S. Yap +10 more
TL;DR: It is proposed that contractile stress transmitted from the apoptotic cell through E-cadherin adhesions elicits a mechanosensitive response in neighbor cells that is necessary for the morphogenetic event of apoptotic extrusion to occur.
Journal ArticleDOI
Cortactin Scaffolds Arp2/3 and WAVE2 at the Epithelial Zonula Adherens
Siew Ping Han,Yann Gambin,Guillermo A. Gomez,Suzie Verma,Nichole Giles,Magdalene Michael,Selwin K. Wu,Zhong Guo,Wayne A. Johnston,Emma Sierecki,Robert G. Parton,Kirill Alexandrov,Alpha S. Yap +12 more
TL;DR: Weed et al. as discussed by the authors identified cortactin as a key scaffold for actin regulation at the zonula adherens, which localizes to the ZA through influences from both E-cadherin and N-WASP.
Journal ArticleDOI
Differential subcellular distributions and trafficking functions of hnRNP A2/B1 spliceoforms
Siew Ping Han,L. Friend,John H. Carson,George Korza,Elisa Barbarese,Michael J. Maggipinto,J. T. Hatfield,Joseph A. Rothnagel,Ross Smith +8 more
TL;DR: It is shown that A2b is the predominant cytoplasmic isoform in neural cells, suggesting that it may play a key role in mRNA trafficking, and highlights the importance of considering isoform‐specific functions for alternatively spliced proteins.