S
Sigurd Ørstavik
Researcher at University of Oslo
Publications - 28
Citations - 1367
Sigurd Ørstavik is an academic researcher from University of Oslo. The author has contributed to research in topics: Protein kinase A & Protein subunit. The author has an hindex of 19, co-authored 28 publications receiving 1322 citations. Previous affiliations of Sigurd Ørstavik include Oslo University Hospital.
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Journal ArticleDOI
Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450.
Oliwia Witczak,Bjørn Steen Skålhegg,Guy Keryer,Michel Bornens,Kjetil Taskén,Tore Jahnsen,Sigurd Ørstavik +6 more
TL;DR: The observation of two mRNAs and several splice products suggests additional functions for the AKAP450 gene, which was shown to co‐purify in centrosomal preparations and localized to centrosomes.
Book ChapterDOI
Structure, function, and regulation of human cAMP-dependent protein kinases.
Kjetil Taskén,Bjørn Steen Skålhegg,Kristin Austlid Taskén,Rigmor Solberg,Helle K. Knutsen,Finn Olav Levy,Mårten Sandberg,Sigurd Ørstavik,Larsen T,Johansen Ak,Vang T,Schrader Hp,Nils Reinton,Torgersen Km,Hansson,Tore Jahnsen +15 more
TL;DR: The existence of a number of anchoring proteins specific to either RIIalpha or RIIbeta, and which localize cAKII isozymes toward distinct substrates at defined subcellular loci, strongly supports the idea that specific functions can be assigned to the various cAK isoz enzymes.
Journal ArticleDOI
Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95.
Turid Eide,Vince Coghlan,Sigurd Ørstavik,Christian Holsve,Rigmor Solberg,Bjørn Steen Skålhegg,Ned J.C. Lamb,Lorene K. Langeberg,Anne Fernandez,John D. Scott,Tore Jahnsen,Kjetil Taskén +11 more
TL;DR: The results show a distinct redistribution of AKAP95 during mitosis, suggesting that the interaction between AKAP 95 and RIIalpha may be cell cycle-dependent.
Journal ArticleDOI
Identification of a human member of the Ly‐49 multigene family
TL;DR: A human cDNA, termed Ly‐ 49L, is described that constitutes the first human member of the Ly‐49 multigene family and contains a premature stop codon and predicts a truncated protein that lacks the distal part of a C‐terminal lectin domain.
Journal ArticleDOI
Characterization of the Human Gene Encoding the Type Iα and Type Iβ cGMP-Dependent Protein Kinase (PRKG1)
TL;DR: The cloning of the gene PRKG1 is described, a single-copy gene consisting of 19 exons encompassing at least 220 kb that was shown to encode the type Iα- and type Iβ-specific parts of the cGK.