Sihan Lin

TL;DR: A series of experiments show that the Mg‐enriched microenvironment not only stimulates the osteogenic differentiation of stem cells but also promotes neovascularization, suggesting that biomaterials mimicking the developmental microenvironment might be promising tools to enhance tissue regeneration.

TL;DR: Extensive vascularized bone regeneration in the femoral defects of rats revealed that the use of Mg particles as the foaming agent is feasible, endowing injectable hydrogels with optimized porosity and enhanced bioactivity, and providing a new strategy for future designs of porous hydrogel in tissue engineering.

TL;DR: In this paper, a photo-cross-linking hydrogel adhesive is developed inspired by the success of light-curing techniques in dentistry, which operates on a fast (within 5 s) phototriggered S-nitrosylation coupling reaction and employs imine anchoring to connect to host tissues.

TL;DR: In this article, a bilayer scaffold combined with a photocurable silk sealant for osteochondral repair is reported, and the results demonstrate that the new approach of marginal sealing around the cartilage layer with Sil-MA hydrogel has tremendous potential for clinical use.

TL;DR: 3D-printed silk-based scaffolds with sustained release of copper peptide, a copper ion-specific binding tripeptide, were fabricated and exhibited similar therapeutic effects to free copper ions, with lower toxicity.