S
Simon Fishel
Researcher at University of Nottingham
Publications - 106
Citations - 4468
Simon Fishel is an academic researcher from University of Nottingham. The author has contributed to research in topics: Embryo transfer & Pregnancy. The author has an hindex of 31, co-authored 102 publications receiving 3992 citations. Previous affiliations of Simon Fishel include Liverpool John Moores University & University of Cambridge.
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Journal ArticleDOI
Self-organization of the human embryo in the absence of maternal tissues
Marta N. Shahbazi,Agnieszka Jedrusik,Sanna Vuoristo,Gaëlle Recher,Gaëlle Recher,Anna Hupalowska,Virginia N. Bolton,Norah M. E. Fogarty,Alison Campbell,Liani Devito,Dusko Ilic,Yakoub Khalaf,Kathy K. Niakan,Simon Fishel,Magdalena Zernicka-Goetz +14 more
TL;DR: Using human embryos and human pluripotent stem cells, it is shown that the reorganization of the embryonic lineage is mediated by cellular polarization leading to cavity formation, indicating that the critical remodelling events at this stage of human development are embryo-autonomous.
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Modelling a risk classification of aneuploidy in human embryos using non-invasive morphokinetics
TL;DR: No significant differences were observed in first or second cell-cycle length, synchrony of the second or third cell cycles, duration of blastulation, multinucleation at the 2-cell stage and irregular division patterns between euploid and aneuploid embryos.
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In vitro fertilization: a treatment for male infertility
Jacques Cohen,Robert G Edwards,Carole B. Fehilly,Simon Fishel,Jonathan Hewitt,J. M. Purdy,George F. Rowland,P. C. Steptoe,John Webster +8 more
TL;DR: The collection of split ejaculates and the careful preparation of spermatozoa, by sedimentation and layering methods, proved to be beneficial, improving sperm motility and raising the chance of fertilization.
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Human chorionic gonadotropin secreted by preimplantation embryos cultured in vitro
TL;DR: Human oocytes were collected by laparoscopy and fertilized and cultured in vitro and human chorionic gonadotropin was detected in the medium surrounding two embryos cultured for more than 7 days after fertilization.
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Retrospective analysis of outcomes after IVF using an aneuploidy risk model derived from time-lapse imaging without PGS
Alison Campbell,Simon Fishel,Natalie Bowman,Samantha Duffy,Mark Sedler,Simon Thornton. Alison Campbell,Simon Thornton +6 more
TL;DR: The clinical relevance of the aneuploidy risk classification model is demonstrated and a novel, non-invasive method of embryo selection to yield higher implantation and live birth rates without PGS is introduced.