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Simon G. Danby

Researcher at University of Sheffield

Publications -  58
Citations -  1891

Simon G. Danby is an academic researcher from University of Sheffield. The author has contributed to research in topics: Atopic dermatitis & Transepidermal water loss. The author has an hindex of 18, co-authored 49 publications receiving 1492 citations. Previous affiliations of Simon G. Danby include Royal Hallamshire Hospital & University of Central Lancashire.

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Epidermal Barrier Dysfunction in Atopic Dermatitis

TL;DR: The strong association between both genetic barrier defects and environmental insults to the barrier with AD suggests that epidermal barrier dysfunction is a primary event in the development of this disease.
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Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care.

TL;DR: Topical application of olive oil caused a significant reduction in stratum corneum integrity and induced mild erythema in volunteers with and without a history of atopic dermatitis, challenging the unfounded belief that all natural oils are beneficial for the skin.
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Research Techniques Made Simple: Transepidermal Water Loss Measurement as a Research Tool

TL;DR: How to optimally use TEWL measurements as a skin research tool in vivo and in Vitro is described.
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Skin barrier breakdown: a renaissance in emollient therapy.

TL;DR: This new understanding of how breakdown of the skin barrier is the first event in the development of atopic eczema provides a rationale for a renaissance in the use of a complete emollient therapy regimen in atopic Eczema and related skin barrier breakdown diseases, such as asteatotic ecZema and irritant contact dermatitis.
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The effect of aqueous cream BP on the skin barrier in volunteers with a previous history of atopic dermatitis.

TL;DR: The emollient aqueous cream BP is frequently used for the treatment of atopic dermatitis, yet it is associated with a high rate of adverse cutaneous reactions, and contains the harsh anionic surfactant sodium lauryl sulphate.