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Simon Murch

Researcher at University of Warwick

Publications -  86
Citations -  8359

Simon Murch is an academic researcher from University of Warwick. The author has contributed to research in topics: Enteropathy & T cell. The author has an hindex of 30, co-authored 85 publications receiving 6860 citations. Previous affiliations of Simon Murch include University Hospital Coventry.

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Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect

TL;DR: The meta-analyses indicate protection against child infections and malocclusion, increases in intelligence, and probable reductions in overweight and diabetes, and an increase in tooth decay with longer periods of breastfeeding.
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Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease

TL;DR: Frequency of TNF-α secreting cells is significantly increased in the mucosa of inflamed intestine, regardless of pathogenesis, and higher levels are seen in patients with IBD than in UC, probably reflecting the extensive T-cell activation in Crohn's disease.
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Retraction of an interpretation

TL;DR: Ten of the 12 original authors of the Early Report “Ileal-lymphoidnodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children”, published in The Lancet in 1998 are considering together formally retract the interpretation placed upon these findings in the paper.
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Management guidelines of eosinophilic esophagitis in childhood.

TL;DR: EoE is a chronic, relapsing inflammatory disease with largely unquantified long-term consequences, and better maintenance treatment as well as biomarkers for assessing treatment response and predicting long- term complications is urgently needed.
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Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels

TL;DR: It is shown through diversity analysis of the microbial community structure based on the 16S rRNA gene that the gut microbiome of IBD patients is less diverse compared to healthy individuals, and a bacterial family co-abundance network is reconstructed, suggesting highly important groups of bacteria in the gut that can coexist with other bacteria across a range of conditions.