S
Simon Murch
Researcher at University of Warwick
Publications - 86
Citations - 8359
Simon Murch is an academic researcher from University of Warwick. The author has contributed to research in topics: Enteropathy & T cell. The author has an hindex of 30, co-authored 85 publications receiving 6860 citations. Previous affiliations of Simon Murch include University Hospital Coventry.
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Journal ArticleDOI
Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect
Cesar G. Victora,Rajiv Bahl,Aluísio J D Barros,Giovanny Vinícius Araújo de França,Susan Horton,Julia Krasevec,Simon Murch,Mari Jeeva Sankar,Neff Walker,Nigel Rollins +9 more
TL;DR: The meta-analyses indicate protection against child infections and malocclusion, increases in intelligence, and probable reductions in overweight and diabetes, and an increase in tooth decay with longer periods of breastfeeding.
Journal ArticleDOI
Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease
Emma J. Breese,Colin A Michie,S Nicholls,Simon Murch,C B Williams,Paola Domizio,John A. Walker-Smith,Thomas T. MacDonald +7 more
TL;DR: Frequency of TNF-α secreting cells is significantly increased in the mucosa of inflamed intestine, regardless of pathogenesis, and higher levels are seen in patients with IBD than in UC, probably reflecting the extensive T-cell activation in Crohn's disease.
Journal ArticleDOI
Retraction of an interpretation
Simon Murch,Andrew Anthony,David H Casson,Mohsin Malik,M Berelowitz,Amar P. Dhillon,Michael A. Thomson,Alan Valentine,Susan E. Davies,John A. Walker-Smith +9 more
TL;DR: Ten of the 12 original authors of the Early Report “Ileal-lymphoidnodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children”, published in The Lancet in 1998 are considering together formally retract the interpretation placed upon these findings in the paper.
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Management guidelines of eosinophilic esophagitis in childhood.
Alexandra Papadopoulou,Sibylle Koletzko,Robert Heuschkel,J. A. Dias,Katrina J. Allen,Simon Murch,Sonny K. F. Chong,Frédéric Gottrand,Steffen Husby,Paolo Lionetti,M. L. Mearin,Frank M. Ruemmele,Michela Schäppi,Annamaria Staiano,Michael Wilschanski,Yvan Vandenplas +15 more
TL;DR: EoE is a chronic, relapsing inflammatory disease with largely unquantified long-term consequences, and better maintenance treatment as well as biomarkers for assessing treatment response and predicting long- term complications is urgently needed.
Journal ArticleDOI
Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels
Mohammad Tauqeer Alam,Gregory C. A. Amos,Gregory C. A. Amos,Andrew R. J. Murphy,Simon Murch,Elizabeth M. H. Wellington,Ramesh P. Arasaradnam +6 more
TL;DR: It is shown through diversity analysis of the microbial community structure based on the 16S rRNA gene that the gut microbiome of IBD patients is less diverse compared to healthy individuals, and a bacterial family co-abundance network is reconstructed, suggesting highly important groups of bacteria in the gut that can coexist with other bacteria across a range of conditions.