Simona Nicolini

TL;DR: The catalytic activity of inexpensive copper(II) chloride allows the direct synthesis of mono-, bi-, and tricyclic 4,5-dihydropyrazole-5-carboxylic acid derivatives in a process that circumvents the use of an anhydrous and inert atmosphere.

TL;DR: The hydrazone side chain introduced by the conjugated heterodiene system at the 5-position of the heterocycle represents a valuable functionality for accessing novel 5-acyl derivatives difficult to obtain by other methods.

TL;DR: In this article, the zinc(II) triflate-catalyzed synthesis of highly functionalized pyrroles is described, which involves the preliminary preparation of a- aminohydrazones by the addition of primary amines to 1,2-diaza-1,3-dienes.

TL;DR: The experimental second-order rate constants for the reactions of 1a-d with amines 3 and triarylphosphines 4 agreed with those calculated from E, N, and s, indicating the applicability of the linear free energy relationship for predicting potential nucleophilic reaction partners of 1,2-diaza-1,3-dienes 1.

TL;DR: In this article, a regioselective inverse-electron-demand hetero-Diels-Alder reaction of in situ generated 1,2-diaza-1,3-dienes with methoxyallene is reported.