Simone Miller

TL;DR: Crosstalk between lymphoid tissue–inducer cells and stromal cells is reactivated in adults to maintain secondary lymphoid organ integrity and thereby contributes to the preservation of immunocompetence.

TL;DR: The data indicate that chronic immune reactivity against pathogen-derived antigens persisting in the vasculature significantly exacerbates atherogenesis.

TL;DR: In this article, the authors assessed the antigen-presenting capacity of endothelial cells (ECs) in vivo using a transgenic mouse model with β-galactosidase (β-gal) expression confined to the vascular endothelium (Tie2-LacZ mice).

TL;DR: It is revealed that IFNGR signaling in ECs activates a potent peripheral negative feedback circuit that protects vascularized grafts from occlusive TV.

TL;DR: It is reported here that the intraocular administration of the neurotropic LCMV strain Armstrong (Arm) elicited pronounced chorioretinitis and keratitis and that infection with the more viscerotropic strains THE AUTHORS and Docile precipitated less severe immunopathological ocular disease.