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Beatrice Bolinger
Researcher at University of St. Gallen
Publications - 9
Citations - 622
Beatrice Bolinger is an academic researcher from University of St. Gallen. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 6, co-authored 9 publications receiving 595 citations.
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Journal ArticleDOI
Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.
Elke Scandella,Beatrice Bolinger,Evelyn Lattmann,Simone Miller,Stéphanie Favre,Dan R. Littman,Daniela Finke,Sanjiv A. Luther,Tobias Junt,Tobias Junt,Burkhard Ludewig +10 more
TL;DR: Crosstalk between lymphoid tissue–inducer cells and stromal cells is reactivated in adults to maintain secondary lymphoid organ integrity and thereby contributes to the preservation of immunocompetence.
Journal ArticleDOI
Aggravation of viral hepatitis by platelet-derived serotonin
Philipp A. Lang,Claudio Contaldo,Panco Georgiev,Ashraf Mohammad El-Badry,Mike Recher,Michael O. Kurrer,Luisa Cervantes-Barragan,Burkhard Ludewig,Thomas Calzascia,Beatrice Bolinger,Doron Merkler,Doron Merkler,Bernhard Odermatt,Michael Bader,Rolf Graf,Pierre-Alain Clavien,Ahmed N. Hegazy,Ahmed N. Hegazy,Max Löhning,Max Löhning,Nicola L. Harris,Pamela S. Ohashi,Hans Hengartner,Rolf M. Zinkernagel,Karl S. Lang,Karl S. Lang +25 more
TL;DR: Serotonin treatment of infected mice delayed entry of activated CD8+ T cells into the liver, delayed virus control and aggravated immunopathological hepatitis, suggesting vasoactive serotonin supports virus persistence in the liver and aggravates virus-induced immunopathology.
Journal ArticleDOI
Chronic Immune Reactivity Against Persisting Microbial Antigen in the Vasculature Exacerbates Atherosclerotic Lesion Formation
Philippe Krebs,Elke Scandella,Beatrice Bolinger,Daniel S. Engeler,Simone Miller,Burkhard Ludewig +5 more
TL;DR: The data indicate that chronic immune reactivity against pathogen-derived antigens persisting in the vasculature significantly exacerbates atherogenesis.
Journal ArticleDOI
Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen
Beatrice Bolinger,Philippe Krebs,Yinghua Tian,Daniel S. Engeler,Elke Scandella,Simone Miller,Douglas C. Palmer,Nicholas P. Restifo,Pierre-Alain Clavien,Burkhard Ludewig +9 more
TL;DR: In this article, the authors assessed the antigen-presenting capacity of endothelial cells (ECs) in vivo using a transgenic mouse model with β-galactosidase (β-gal) expression confined to the vascular endothelium (Tie2-LacZ mice).
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IFN‐γ‐receptor signaling ameliorates transplant vasculopathy through attenuation of CD8+ T‐cell‐mediated injury of vascular endothelial cells
Beatrice Bolinger,Daniel S. Engeler,Philippe Krebs,Simone Miller,Sonja Firner,Matthias W. Hoffmann,Douglas C. Palmer,Nicholas P. Restifo,Yinghua Tian,Pierre-Alain Clavien,Burkhard Ludewig,Burkhard Ludewig,Burkhard Ludewig +12 more
TL;DR: It is revealed that IFNGR signaling in ECs activates a potent peripheral negative feedback circuit that protects vascularized grafts from occlusive TV.