S
Sing Yian Chew
Researcher at Nanyang Technological University
Publications - 96
Citations - 5900
Sing Yian Chew is an academic researcher from Nanyang Technological University. The author has contributed to research in topics: Regeneration (biology) & Neural tissue engineering. The author has an hindex of 30, co-authored 89 publications receiving 5068 citations. Previous affiliations of Sing Yian Chew include Johns Hopkins University & Singapore–MIT alliance.
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Sustained release of proteins from electrospun biodegradable fibers.
TL;DR: This study investigated the feasibility of encapsulating human beta-nerve growth factor (NGF), which was stabilized in a carrier protein, bovine serum albumin (BSA) in a copolymer of epsilon-caprolactone and ethyl ethylene phosphate (PCLEEP) by electrospinning to produce biofunctional tissue scaffolds.
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The Effect of the Alignment of Electrospun Fibrous Scaffolds on Schwann Cell Maturation
TL;DR: Aligned electrospun poly(epsilon-caprolactone) (PCL) fibers were fabricated to test their potential to provide contact guidance to human Schwann cells and confirmed the propensity of aligned fibers in promoting Schwann cell maturation.
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Aligned Protein–Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform†
TL;DR: It is demonstrated that, without further modification, plain electrospun fibers can help in peripheral nerve regeneration; however, the synergistic effect of an encapsulated growth factor facilitated a more significant recovery.
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Current applications and future perspectives of artificial nerve conduits
TL;DR: This review highlights the recent advances in synthetic nerve guide designs for peripheral nerve regeneration, and the in vivo applicability and future prospects of these nerve guide conduits.
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The application of nanofibrous scaffolds in neural tissue engineering.
TL;DR: Sub-micron and nano-scale fibrous scaffolds which mimic the topography of natural extracellular matrix (ECM) can be potential scaffold candidates for neural tissue engineering.