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Sofia Svedhem
Researcher at Chalmers University of Technology
Publications - 63
Citations - 2257
Sofia Svedhem is an academic researcher from Chalmers University of Technology. The author has contributed to research in topics: Lipid bilayer & Quartz crystal microbalance. The author has an hindex of 25, co-authored 63 publications receiving 2049 citations. Previous affiliations of Sofia Svedhem include SP Technical Research Institute of Sweden.
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Cell membrane damage and protein interaction induced by copper containing nanoparticles--importance of the metal release process.
Hanna L. Karlsson,Pontus Cronholm,Yolanda Hedberg,Malin Tornberg,Laura de Battice,Sofia Svedhem,Inger Odnevall Wallinder +6 more
TL;DR: Results of this study suggest that the observed membrane damage is caused by the metal release process at the cell membrane surface and highlight differences in reactivity between metallic nanoparticles of Cu and Cu-Zn and nano and micron-sized Cu metal particles.
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Graphene Oxide and Lipid Membranes: Interactions and Nanocomposite Structures
TL;DR: Graphene oxide-induced rupture of preadsorbed liposomes and the formation of a nanocomposite, bio-nonbio multilayer structure, consisting of alternating graphene oxide monolayers and lipid membranes are discovered.
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Patterns of DNA-Labeled and scFv-Antibody-Carrying Lipid Vesicles Directed by Material-Specific Immobilization of DNA and Supported Lipid Bilayer Formation on an Au/SiO2 Template
Sofia Svedhem,Indriati Pfeiffer,Charlotte Larsson,Christer Wingren,Carl A.K. Borrebaeck,Fredrik Höök +5 more
TL;DR: Supporting phosphatidylcholine lipid bilayers have emerged as interesting candidate substrates for protein chips, since they efficiently reduce nonspecific protein adsorption 5 and, at the same time, allow different strategies for protein immobilization with biospecific water.
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The Inflammation-associated Protein TSG-6 Cross-links Hyaluronan via Hyaluronan-induced TSG-6 Oligomers
Natalia S. Baranova,Erik Nilebäck,F. Michael Haller,David Briggs,Sofia Svedhem,Anthony J. Day,Ralf P. Richter +6 more
TL;DR: It is found that full-length TSG-6 binds with pronounced positive cooperativity and can cross-link HA at physiologically relevant concentrations, and it is proposed that condensation is the result of protein-mediated HA cross-linking.
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QCM-D and reflectometry instrument: applications to supported lipid structures and their biomolecular interactions.
Malin Edvardsson,Sofia Svedhem,Guoliang Wang,Ralf P. Richter,Michael Rodahl,Bengt Herbert Kasemo +5 more
TL;DR: A novel setup was recently developed, combining quartz crystal microbalance with dissipation monitoring (QCM-D) and optical reflectometry for measurements on one and the same surface of biomolecular adlayers and interactions, demonstrating three major advantages of the combination instrument.