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Sofia Svedhem

Researcher at Chalmers University of Technology

Publications -  63
Citations -  2257

Sofia Svedhem is an academic researcher from Chalmers University of Technology. The author has contributed to research in topics: Lipid bilayer & Quartz crystal microbalance. The author has an hindex of 25, co-authored 63 publications receiving 2049 citations. Previous affiliations of Sofia Svedhem include SP Technical Research Institute of Sweden.

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Cell membrane damage and protein interaction induced by copper containing nanoparticles--importance of the metal release process.

TL;DR: Results of this study suggest that the observed membrane damage is caused by the metal release process at the cell membrane surface and highlight differences in reactivity between metallic nanoparticles of Cu and Cu-Zn and nano and micron-sized Cu metal particles.
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Graphene Oxide and Lipid Membranes: Interactions and Nanocomposite Structures

TL;DR: Graphene oxide-induced rupture of preadsorbed liposomes and the formation of a nanocomposite, bio-nonbio multilayer structure, consisting of alternating graphene oxide monolayers and lipid membranes are discovered.
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Patterns of DNA-Labeled and scFv-Antibody-Carrying Lipid Vesicles Directed by Material-Specific Immobilization of DNA and Supported Lipid Bilayer Formation on an Au/SiO2 Template

TL;DR: Supporting phosphatidylcholine lipid bilayers have emerged as interesting candidate substrates for protein chips, since they efficiently reduce nonspecific protein adsorption 5 and, at the same time, allow different strategies for protein immobilization with biospecific water.
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The Inflammation-associated Protein TSG-6 Cross-links Hyaluronan via Hyaluronan-induced TSG-6 Oligomers

TL;DR: It is found that full-length TSG-6 binds with pronounced positive cooperativity and can cross-link HA at physiologically relevant concentrations, and it is proposed that condensation is the result of protein-mediated HA cross-linking.
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QCM-D and reflectometry instrument: applications to supported lipid structures and their biomolecular interactions.

TL;DR: A novel setup was recently developed, combining quartz crystal microbalance with dissipation monitoring (QCM-D) and optical reflectometry for measurements on one and the same surface of biomolecular adlayers and interactions, demonstrating three major advantages of the combination instrument.