Solomon Yap

TL;DR: Blood vessel walls harbor a reserve of progenitor cells that may be integral to the origin of the elusive MSCs and other related adult stem cells.

TL;DR: This work demonstrates the co-existence of 2 separate perivascular MSC progenitors: pericytes in capillaries and microvessels and adventitial cells around larger vessels.

TL;DR: Myoendothelial cells regenerate myofibers in the injured skeletal muscle of severe combined immunodeficiency mice more effectively than CD56+ myogenic progenitors, are amenable to biotechnological handling, including purification by flow cytometry and long-term expansion in vitro, and may have potential for the treatment of human muscle disease.

TL;DR: The existence in human skeletal muscle and the prospective isolation of progenitor cells with a high potential for UCP1 expression are shown for the first time and the discovery of this reservoir generates a new hope of treating obesity by acting on energy dissipation.

TL;DR: A rare subset of myoendothelial cells that express markers of both endothelial and myogenic cell lineages and exhibit dramatic myogenic and cardiomyogenic potential has been identified and purified from skeletal muscle.