S
Spencer K. Koerner
Researcher at Cedars-Sinai Medical Center
Publications - 42
Citations - 6212
Spencer K. Koerner is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Pulmonary hypertension & Transplantation. The author has an hindex of 23, co-authored 42 publications receiving 6030 citations. Previous affiliations of Spencer K. Koerner include University of California, Los Angeles.
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Journal ArticleDOI
A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension
Robyn J. Barst,Lewis J. Rubin,Walker Long,Michael D. McGoon,Stuart Rich,David B. Badesch,Bertron M. Groves,Victor F. Tapson,Robert C. Bourge,Bruce H. Brundage,Spencer K. Koerner,David Langleben,Cesar A. Keller,Srinivas Murali,Barry F. Uretsky,Linda M. Clayton,Maria M. Jöbsis,Shelmer D. Blackburn,Denise Shortino,James W. Crow +19 more
TL;DR: As compared with conventional therapy, the continuous intravenous infusion of epoprostenol produced symptomatic and hemodynamic improvement, as well as improved survival in patients with severe primary pulmonary hypertension.
Journal ArticleDOI
Primary pulmonary hypertension: a national prospective study
Stuart Rich,D R Dantzker,S M Ayres,Edward H. Bergofsky,Bruce H. Brundage,Katherine M. Detre,Alfred P. Fishman,Roberta M. Goldring,Bertron M. Groves,Spencer K. Koerner +9 more
TL;DR: Although no deaths or sustained morbid events occurred during the diagnostic evaluation of the patients, the typically long interval from initial symptoms to diagnosis emphasizes the need to develop strategies to make the diagnosis earlier.
Journal ArticleDOI
Effects of Long-term Infusion of Prostacyclin (Epoprostenol) on Echocardiographic Measures of Right Ventricular Structure and Function in Primary Pulmonary Hypertension
Alan L. Hinderliter,Park W. Willis,Robyn J. Barst,Stuart Rich,Lewis J. Rubin,David B. Badesch,Berton M. Groves,Michael D. McGoon,Victor F. Tapson,Robert C. Bourge,Bruce H. Brundage,Spencer K. Koerner,David Langleben,Cesar A. Keller,Srinivas Murali,Barry F. Uretsky,Gary G. Koch,Shu Li,Linda M. Clayton,Maria M. Jöbsis,Shelmer D. Blackburn,James W. Crow,Walker Long +22 more
TL;DR: The echocardiographic characteristics of participants in this trial; the relationships of echOCardiographic variables to hemodynamic parameters, exercise capacity, and quality of life; and the echoprostenol changes associated with prostacyclin therapy are described.
Journal Article
Effects of long-term infusion of prostacyclin (epoprostenol) on echocardiographic measures of right ventricular structure and function in primary pulmonary hypertension
Alan L. Hinderliter,Park W. Willis,Robyn J. Barst,Stuart Rich,Lewis J. Rubin,David B. Badesch,Berton M. Groves,Michael D. McGoon,Victor F. Tapson,Robert C. Bourge,Bruce H. Brundage,Spencer K. Koerner,David Langleben,Cesar A. Keller,Srinivas Murali,Barry F. Uretsky,Gary G. Koch,Shu Li,Linda M. Clayton,Maria M. Jöbsis,Shelmer D. Blackburn,James W. Crow,Walker Long +22 more
TL;DR: In a recent prospective randomized study of severely symptomatic patients, treatment with prostacyclin (epoprostenol) produced improvements in hemodynamics, quality of life, and survival as mentioned in this paper.
Journal ArticleDOI
Gastric Intramural pH as a Predictor of Success or Failure in Weaning Patients from Mechanical Ventilation
TL;DR: The hypothesis that gastric pHi can be used as a rapid indicator of blood-flow diversion from the splanchnic bed in patients in whom the demands of the respiratory pump during weaning trials are excessive or who have inadequate oxygen delivery to meet these demands is tested.