S
Spencer V. Muse
Researcher at North Carolina State University
Publications - 36
Citations - 11089
Spencer V. Muse is an academic researcher from North Carolina State University. The author has contributed to research in topics: Nonsynonymous substitution & Gene. The author has an hindex of 26, co-authored 36 publications receiving 9992 citations. Previous affiliations of Spencer V. Muse include Pennsylvania State University & University of Missouri.
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Journal ArticleDOI
PowerMarker: an integrated analysis environment for genetic marker analysis
Kejun Liu,Spencer V. Muse +1 more
TL;DR: PowerMarker delivers a data-driven, integrated analysis environment (IAE) for genetic data that accelerates the analysis lifecycle and enables users to maintain data integrity throughout the process.
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HyPhy: hypothesis testing using phylogenies
TL;DR: The HyPhypackage is designed to provide a flexible and unified platform for carrying out likelihood-based analyses on multiple alignments of molecular sequence data, with the emphasis on studies of rates and patterns of sequence evolution.
Journal ArticleDOI
A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome.
Spencer V. Muse,Brandon S. Gaut +1 more
TL;DR: Simulations help confirm previous suggestions that silent sites are saturated, leaving no evidence of heterogeneity in synonymous substitution rates, and confirm previous findings that substitution rates in the chloroplast genome are subject to both lineage-specific and locus-specific effects.
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Genetic Structure and Diversity Among Maize Inbred Lines as Inferred From DNA Microsatellites
Kejun Liu,Major M. Goodman,Spencer V. Muse,J. Stephen C. Smith,Edward S. Buckler,John Doebley +5 more
TL;DR: Comparison of diversity in equivalent samples of inbreds and open-pollinated landraces revealed that maize in breds capture <80% of the alleles in the landrace, suggesting that landraced animals can provide additional genetic diversity for maize breeding.
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Datamonkey 2.0: A Modern Web Application for Characterizing Selective and Other Evolutionary Processes.
Steven Weaver,Stephen D. Shank,Stephanie J. Spielman,Michael Li,Spencer V. Muse,Sergei L Kosakovsky Pond +5 more
TL;DR: The release ofDatamonkey 2.0, a completely re-engineered version of the Datamonkey web-server for analyzing evolutionary signatures in sequence data, and HyPhy Vision, an accompanying JavaScript application for visualizing analysis results.