S
Spiros Miyakis
Researcher at Wollongong Hospital
Publications - 55
Citations - 7836
Spiros Miyakis is an academic researcher from Wollongong Hospital. The author has contributed to research in topics: Bone disease & Daptomycin. The author has an hindex of 20, co-authored 53 publications receiving 6810 citations. Previous affiliations of Spiros Miyakis include Aristotle University of Thessaloniki & Illawarra Health & Medical Research Institute.
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Journal ArticleDOI
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).
Spiros Miyakis,Michael D. Lockshin,Tatsuya Atsumi,D W Branch,Robin L. Brey,Ricard Cervera,R. H. W. M. Derksen,P. G. De Groot,Takao Koike,Pier Luigi Meroni,Guido Reber,Yehuda Shoenfeld,Angela Tincani,Panayiotis G. Vlachoyiannopoulos,Steven A. Krilis +14 more
TL;DR: This document appraise the existing evidence on clinical and laboratory features of APS addressed during the forum and proposes amendments to the Sapporo criteria, including definitions on features ofAPS that were not included in the updated criteria.
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Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance A Randomized Clinical Trial
Patrick N A Harris,Patrick N A Harris,Patrick N A Harris,Paul A. Tambyah,David C. Lye,David C. Lye,David C. Lye,Yin Mo,Tau H. Lee,Tau H. Lee,Tau H. Lee,Mesut Yilmaz,Thamer H. Alenazi,Yaseen M. Arabi,Marco Falcone,Matteo Bassetti,Elda Righi,Benjamin A. Rogers,Souha S. Kanj,Hasan Bhally,Jon Iredell,Jon Iredell,Marc Mendelson,Tom H. Boyles,David Looke,David Looke,Spiros Miyakis,Spiros Miyakis,Spiros Miyakis,Genevieve Walls,Mohammed Al Khamis,Ahmed Zikri,Amy Crowe,Paul R. Ingram,Paul R. Ingram,Nick Daneman,Paul M. Griffin,Paul M. Griffin,Paul M. Griffin,Eugene Athan,Penelope Lorenc,Peter Baker,Leah W. Roberts,Scott A. Beatson,Anton Y. Peleg,Anton Y. Peleg,Tiffany Harris-Brown,David L. Paterson,David L. Paterson +48 more
TL;DR: Among patients with E coli or K pneumoniae bloodstream infection and ceftriaxone resistance, definitive treatment with piperacillin-tazobactam compared with meropenem did not result in a noninferior 30-day mortality, and findings do not support use of piperACillin- tazobactsam in this setting.
Journal ArticleDOI
Whole Genome Characterization of the Mechanisms of Daptomycin Resistance in Clinical and Laboratory Derived Isolates of Staphylococcus aureus
Anton Y. Peleg,Spiros Miyakis,Spiros Miyakis,Doyle V. Ward,Ashlee M. Earl,Aileen Rubio,David R. Cameron,Satish K. Pillai,Satish K. Pillai,Robert C. Moellering,Robert C. Moellering,George M. Eliopoulos,George M. Eliopoulos +12 more
TL;DR: Point mutations in genes coding for membrane phospholipids are associated with the development of reduced susceptibility to daptomycin in S. aureus.
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Voriconazole concentrations and outcome of invasive fungal infections
TL;DR: The data suggest that voriconazole TDM is appropriate for all patients as soon as steady state is achieved, and for non-responding patients with low trough concentrations, the association with IFI-related mortality indicates the need for dose adjustments to achieve and sustain voriconsazole concentrations.
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Beta 2 glycoprotein I--function in health and disease
TL;DR: It has been demonstrated that beta2GPI binds factor (F) XI in vitro at concentrations lower than those of the protein in human plasma, and this binding inhibits FXI activation to FXIa by thrombin and FXIIa.