S
Stefan Karlsson
Researcher at Lund University
Publications - 303
Citations - 20537
Stefan Karlsson is an academic researcher from Lund University. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 70, co-authored 292 publications receiving 19180 citations. Previous affiliations of Stefan Karlsson include deCODE genetics & Netherlands Cancer Institute.
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Development of gene therapy for blood disorders by gene transfer into haematopoietic stem cells.
TL;DR: Lentiviral vectors have recently emerged as promising vectors for human HSCs because they can transduce dividing and nondividing H SCs efficiently, and may become the vectors of choice in the future for treatment of blood disorders where a large fraction of HSCS has to be corrected.
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Successful Treatment of Metachromatic Leukodystrophy Using Bone Marrow Transplantation of HoxB4 Overexpressing Cells
TL;DR: The idea that hematopoietic stem cells (HSCs) transduced with a HoxB4 expression vector could be the useful carriers of therapeutic proteins into the brain for regeneration of oligodendrocytes to treat such demyelinating disorders as MLD, Krabbe disease, and multiple sclerosis is supported.
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Typology of practices for managing consumer returns in internet retailing
TL;DR: In this article, the authors explore, describe and categorise practices of managing product returns empirically in internet retailing, and identify a mismatch between theory and practice of returns management.
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Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia
Sara E. Sjögren,Kavitha Siva,Shamit Soneji,Amee J George,Amee J George,Amee J George,Marcus Winkler,Pekka Jaako,Marcin W. Wlodarski,Stefan Karlsson,Ross D. Hannan,Ross D. Hannan,Ross D. Hannan,Johan Flygare +13 more
TL;DR: This study determines for the first time that a mouse model of DBA can respond to glucocorticoid treatment, similar to DBA patients, and demonstrates that glucoc Corticoids treatment reduces apoptosis, rescues erythroid progenitor depletion and premature differentiation of erystroid cells.
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SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q-myelodysplastic syndrome.
Kavitha Siva,Pekka Jaako,Kenichi Miharada,Emma Rörby,Mats Ehinger,Göran Karlsson,Stefan Karlsson +6 more
TL;DR: SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q-myelodysplastic syndrome.