S
Stefania Crucitta
Researcher at University of Pisa
Publications - 64
Citations - 1259
Stefania Crucitta is an academic researcher from University of Pisa. The author has contributed to research in topics: Liquid biopsy & Internal medicine. The author has an hindex of 16, co-authored 51 publications receiving 752 citations. Previous affiliations of Stefania Crucitta include University of Florence.
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Journal ArticleDOI
The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients
Marzia Del Re,Elisa Biasco,Stefania Crucitta,Lisa Derosa,Eleonora Rofi,Cinzia Orlandini,Mario Miccoli,Luca Galli,Alfredo Falcone,G. Jenster,Ron H.N. van Schaik,Romano Danesi +11 more
TL;DR: This study demonstrates that plasma-derived exosomal RNA is a reliable source of AR-V7 that can be detected sensitively by ddPCR assay and shows that resistance to hormonal therapy may be predicted by AR-v7, making it a clinically relevant biomarker.
Journal ArticleDOI
PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC
Marzia Del Re,Riccardo Marconcini,Giulia Pasquini,Eleonora Rofi,Caterina Vivaldi,Francesco Bloise,Giuliana Restante,Elena Arrigoni,Chiara Caparello,Maria Grazia Bianco,Stefania Crucitta,Iacopo Petrini,Enrico Vasile,Alfredo Falcone,Romano Danesi +14 more
TL;DR: This corrects the article DOI: 10.1038/bjc2017.85 to BJC 2017, which indicates the paper was originally published in British Journal of Criminal Justice in 2017.
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Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients.
Marzia Del Re,I. Bertolini,Stefania Crucitta,Lorenzo Fontanelli,Eleonora Rofi,Claudia De Angelis,Lucrezia Diodati,Diletta Cavallero,Giulia Gianfilippo,Barbara Salvadori,Stefano Fogli,Alfredo Falcone,Cristian Scatena,Antonio Giuseppe Naccarato,Manuela Roncella,Matteo Ghilli,Riccardo Morganti,Andrea Fontana,Romano Danesi +18 more
TL;DR: In plasma-derived exosomes, high baseline CDK4 mRNA levels are associated with response to palbociclib plus hormonal therapy, while the increase in TK1 and CDK9 mRNA copies/ml is associated with clinical resistance.
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Understanding the Mechanisms of Resistance in EGFR-Positive NSCLC: From Tissue to Liquid Biopsy to Guide Treatment Strategy.
Marzia Del Re,Stefania Crucitta,Giulia Gianfilippo,Antonio Passaro,Iacopo Petrini,Giuliana Restante,Angela Michelucci,Stefano Fogli,Filippo de Marinis,Camillo Porta,Antonio Chella,Romano Danesi +11 more
TL;DR: Liquid biopsy is a non-invasive method able to detect the molecular dynamic changes that occur under the pressure of treatment, and to capture tumor heterogeneity more efficiently than is allowed by tissue biopsy.
Journal ArticleDOI
Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment
Elena Arrigoni,Marzia Del Re,Sara Galimberti,Giuliana Restante,Eleonora Rofi,Stefania Crucitta,Claudia Baratè,Mario Petrini,Romano Danesi,Antonello Di Paolo +9 more
TL;DR: The role of LSCs and stem cell niche in relation to response to pharmacological treatments and the interaction with the bone marrow microenvironment is focused on.