S
Stefania D'Angelo
Researcher at University of Naples Federico II
Publications - 68
Citations - 1946
Stefania D'Angelo is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 20, co-authored 41 publications receiving 1546 citations. Previous affiliations of Stefania D'Angelo include Parthenope University of Naples & Seconda Università degli Studi di Napoli.
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Journal Article
Pharmacokinetics and metabolism of hydroxytyrosol, a natural antioxidant from olive oil.
Stefania D'Angelo,Caterina Manna,Valentina Migliardi,Orazio Mazzoni,Patrizia Morrica,Giovanni Capasso,Gabriele Pontoni,Patrizia Galletti,Vincenzo Zappia +8 more
TL;DR: The pharmacokinetic analysis indicates a fast and extensive uptake of the molecule by the organs and tissues investigated, with a preferential renal uptake, and an intracellular metabolic pathway of exogenously administered DOPET, implying the involvement of catechol-O-methyltransferase, alcohol dehydrogenase, aldehyde dehydrogen enzyme, and phenolsulfotransferase has been proposed.
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Transport mechanism and metabolism of olive oil hydroxytyrosol in Caco-2 cells.
Caterina Manna,Patrizia Galletti,Giovanna Maisto,Valeria Cucciolla,Stefania D'Angelo,Vincenzo Zappia +5 more
TL;DR: The kinetic data demonstrate that [14C]DPE transport occurs via a passive diffusion mechanism and is bidirectional; the calculated apparent permeability coefficient indicates that the molecule is quantitatively absorbed at the intestinal level.
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Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells.
Stefania D'Angelo,Diego Ingrosso,Valentina Migliardi,Alvara Sorrentino,Giovanna Donnarumma,Adone Baroni,Lucia Masella,Maria Antonietta Tufano,Marcello Zappia,Patrizia Galletti +9 more
TL;DR: In this paper, the effects of hydroxytyrosol (DOPET), the major antioxidant compound present in olive oil, on UVA-induced cell damages were investigated, using a human melanoma cell line (M14) as a model system.
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Protective effect of the phenolic fraction from virgin olive oils against oxidative stress in human cells.
Caterina Manna,Stefania D'Angelo,Valentina Migliardi,Evelina Loffredi,Orazio Mazzoni,Patrizia Morrica,Patrizia Galletti,Vincenzo Zappia +7 more
TL;DR: The linear relationship demonstrated between biological effects and antioxidant capacity measured by the FRAP assay allows the use of this rapid colorimetric method in assessing and certifying the antioxidant power of extra virgin olive oil to be proposed.
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Anti-Obesity Effects of Polyphenol Intake: Current Status and Future Possibilities
TL;DR: The association between polyphenols (resveratrol, quercetin, curcumin, and some polyphenolic extracts) and obesity is considered, focusing on human trials, and the data so far obtained encourage the setting of new trials, necessary to validate benefic role ofpolyphenols in obese individuals.