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Valeria Cucciolla

Researcher at Seconda Università degli Studi di Napoli

Publications -  24
Citations -  2166

Valeria Cucciolla is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Resveratrol & Hydroxytyrosol. The author has an hindex of 20, co-authored 24 publications receiving 2071 citations. Previous affiliations of Valeria Cucciolla include National Research Council.

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The protective effect of the olive oil polyphenol (3,4-dihydroxyphenyl)-ethanol counteracts reactive oxygen metabolite-induced cytotoxicity in Caco-2 cells.

TL;DR: Dietary intake of olive oil polyphenols may lower the risk of reactive oxygen metabolite-mediated diseases such as some gastrointestinal diseases and atherosclerosis, and the data demonstrate that (3,4-dihydroxyphenyl)ethanol can act as a biological antioxidant in a cell culture experimental model.
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Resveratrol Arrests the Cell Division Cycle at S/G2 Phase Transition

TL;DR: It is demonstrated that resveratrol causes a complete and reversible cell cycle arrest at the S phase checkpoint, indicating that the G1 --> S transition occurs normally.
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Transport mechanism and metabolism of olive oil hydroxytyrosol in Caco-2 cells.

TL;DR: The kinetic data demonstrate that [14C]DPE transport occurs via a passive diffusion mechanism and is bidirectional; the calculated apparent permeability coefficient indicates that the molecule is quantitatively absorbed at the intestinal level.
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Olive oil hydroxytyrosol protects human erythrocytes against oxidative damages

TL;DR: The data demonstrate that hydroxytyrosol prevents both oxidative alterations, therefore, providing protection against peroxide-induced cytotoxicity in erythrocytes, giving new experimental support to the hypothesis of a protective role played by nonvitamin antioxidant components of virgin olive oil on oxidative stress in human systems.
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Resveratrol: from basic science to the clinic.

TL;DR: It is suggested that resveratrol might be considered an interesting compound in association with more specific target-oriented drugs, due to the scarce interest of pharmaceutical industry.