Stefania D'Angelo

TL;DR: The pharmacokinetic analysis indicates a fast and extensive uptake of the molecule by the organs and tissues investigated, with a preferential renal uptake, and an intracellular metabolic pathway of exogenously administered DOPET, implying the involvement of catechol-O-methyltransferase, alcohol dehydrogenase, aldehyde dehydrogen enzyme, and phenolsulfotransferase has been proposed.

TL;DR: The kinetic data demonstrate that [14C]DPE transport occurs via a passive diffusion mechanism and is bidirectional; the calculated apparent permeability coefficient indicates that the molecule is quantitatively absorbed at the intestinal level.

TL;DR: In this paper, the effects of hydroxytyrosol (DOPET), the major antioxidant compound present in olive oil, on UVA-induced cell damages were investigated, using a human melanoma cell line (M14) as a model system.

TL;DR: The linear relationship demonstrated between biological effects and antioxidant capacity measured by the FRAP assay allows the use of this rapid colorimetric method in assessing and certifying the antioxidant power of extra virgin olive oil to be proposed.

TL;DR: The association between polyphenols (resveratrol, quercetin, curcumin, and some polyphenolic extracts) and obesity is considered, focusing on human trials, and the data so far obtained encourage the setting of new trials, necessary to validate benefic role ofpolyphenols in obese individuals.