다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

[신간의 별자리x] 우리/미술, 그리고 ‘슬픔의 박물관’

Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

Recent developments in the quantitative analysis of complex networks, based largely on graph theory, have been rapidly translated to studies of brain network organization. The brain's structural and functional systems have features of complex networks--such as small-world topology, highly connected hubs and modularity--both at the whole-brain scale of human neuroimaging and at a cellular scale in non-human animals. In this article, we review studies investigating complex brain networks in diverse experimental modalities (including structural and functional MRI, diffusion tensor imaging, magnetoencephalography and electroencephalography in humans) and provide an accessible introduction to the basic principles of graph theory. We also highlight some of the technical challenges and key questions to be addressed by future developments in this rapidly moving field.

Complex brain networks: graph theoretical analysis of structural and functional systems

We report on a generic procedure to steer (target) a network’s dynamics towards a given, desired evolution. The problem is here tackled through a Master Stability Function approach, assessing the stability of the aimed dynamics, and through a selection of nodes to be targeted. We show that the degree of a node is a crucial element in this selection process, and that the targeting mechanism is most effective in heterogeneous scale-free architectures. This makes the proposed approach applicable to the large majority of natural and man-made networked systems.

Targeting the dynamics of complex

We study the localization of spatial dissipative structures in a nonlinear system formed by a liquid crystal light valve closed in an optical feedback loop. After reviewing the transition from patterns extended across the whole wavefront to localized structures, we investigate how stability and shape of the observed patterns depend on experimental parameters. Interactions between these “dissipative solitons” lead to the formation of several molecule‐like bound states, formed by pairs of localized structures. This fact is explored experimentally and justified theoretically.

Localized structures in nonlinear optics: spatial features and interactions

Abstract The interactions between the components of many real-world systems are best modelled by networks with multiple layers. Different theories have been proposed to explain how multilayered connections affect the linear stability of synchronization in dynamical systems. However, the resulting equations are computationally expensive, and therefore difficult, if not impossible, to solve for large systems. To bridge this gap, we develop a mean-field theory of synchronization for networks with multiple interaction layers. By assuming quasi-identical layers, we obtain accurate assessments of synchronization stability that are comparable with the exact results. In fact, the accuracy of our theory remains high even for networks with very dissimilar layers, thus posing a general question about the mean-field nature of synchronization stability in multilayer networks. Moreover, the computational complexity of our approach is only quadratic in the number of nodes, thereby allowing the study of systems whose investigation was thus far precluded. 

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Mean-field nature of synchronization stability in networks with multiple interaction layers

A wealth of evidence shows that real world networks are endowed with the small-world property i.e., that the maximal distance between any two of their nodes scales logarithmically rather than linearly with their size. In addition, most social networks are organized so that no individual is more than six connections apart from any other, an empirical regularity known as the six degrees of separation. Why social networks have this ultra-small world organization, whereby the graph's diameter is independent of the network size over several orders of magnitude, is still unknown. We show that the 'six degrees of separation' are the property featured by the equilibrium state of any network where individuals weigh between their aspiration to improve their centrality and the costs incurred in forming and maintaining connections. We show, moreover, that the emergence of such a regularity is compatible with all other features, such as clustering and scale-freeness, that normally characterize the structure of social networks. Thus, our results show how simple evolutionary rules of the kind traditionally associated with human cooperation and altruism can also account for the emergence of one of the most intriguing attributes of social networks.

Why are there six degrees of separation in a social network?

A collection of connected phase oscillators, initially unsynchronised, are subjected to a growing process. In such a process, pacemaker oscillators attach to the original network following an exclusively dynamical criterion oriented to entrain the network. Under these conditions, we show that successful entrainment always corresponds to the generation of a scale-free topology in the original graph.

Stefano Boccaletti

Papers

Targeting the dynamics of complex

Localized structures in nonlinear optics: spatial features and interactions

Mean-field nature of synchronization stability in networks with multiple interaction layers

Why are there six degrees of separation in a social network?

Generation of scale-free topology in complex networks by phase entrainment