다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

[신간의 별자리x] 우리/미술, 그리고 ‘슬픔의 박물관’

Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

Recent developments in the quantitative analysis of complex networks, based largely on graph theory, have been rapidly translated to studies of brain network organization. The brain's structural and functional systems have features of complex networks--such as small-world topology, highly connected hubs and modularity--both at the whole-brain scale of human neuroimaging and at a cellular scale in non-human animals. In this article, we review studies investigating complex brain networks in diverse experimental modalities (including structural and functional MRI, diffusion tensor imaging, magnetoencephalography and electroencephalography in humans) and provide an accessible introduction to the basic principles of graph theory. We also highlight some of the technical challenges and key questions to be addressed by future developments in this rapidly moving field.

Complex brain networks: graph theoretical analysis of structural and functional systems

Active control of the synchronization manifold in a ring of mutually coupled oscillators

Many diseases have a genetic origin, and a great effort is being made to detect the genes that are responsible for their insurgence. One of the most promising techniques is the analysis of genetic information through the use of complex networks theory. Yet, a practical problem of this approach is its computational cost, which scales as the square of the number of features included in the initial dataset. In this paper, we propose the use of an iterative feature selection strategy to identify reduced subsets of relevant features, and show an application to the analysis of congenital Obstructive Nephropathy. Results demonstrate that, besides achieving a drastic reduction of the computational cost, the topologies of the obtained networks still hold all the relevant information, and are thus able to fully characterize the severity of the disease.

Preprocessing and analyzing genetic data with complex networks: An application to Obstructive Nephropathy

We introduce the concept of decision cost of a spatial graph, which measures the disorder of a given network taking into account not only the connections between nodes but their position in a two-dimensional map. The influence of the network size is evaluated and we show that normalization of the decision cost allows us to compare the degree of disorder of networks of different sizes. Under this framework, we measure the disorder of the connections between airports of two different countries and obtain some conclusions about which of them is more disordered. The introduced concepts (decision cost and disorder of spatial networks) can easily be extended to Euclidean networks of higher dimensions, and also to networks whose nodes have a certain fitness property (i.e., one-dimensional).

/pdf/disorder-and-decision-cost-in-spatial-networks-2w64035trp.pdf

Disorder and decision cost in spatial networks.

In real-world networked systems, the underlying structure is often affected by external and internal unforeseen factors, making its evolution typically inaccessible. An adaptive strategy was introduced for maintaining synchronization on unpredictably evolving networks [Sorrentino and Ott, Phys. Rev. Lett. 100, 114101 (2008)PRLTAO0031-900710.1103/PhysRevLett.100.114101], which yet does not consider the noise disturbances widely existing in networks' environments. We provide here strategies to control dynamical synchronization on slowly and unpredictably evolving networks subjected to noise disturbances which are observed at the node and at the communication channel level. With our strategy, the nodes' coupling strength is adaptively adjusted with the aim of controlling synchronization, and according only to their received signal and noise disturbances. We first provide a theoretical analysis of the control scheme by introducing an error potential function to seek for the minimization of the synchronization error. Then, we show numerical experiments which verify our theoretical results. In particular, it is found that our adaptive strategy is effective even for the case in which the dynamics of the uncontrolled network would be explosive (i.e., the states of all the nodes would diverge to infinity).

Adaptive control of dynamical synchronization on evolving networks with noise disturbances.

We discuss the emergence of a collective phase locked state in an open chain of N unidirectionally weakly coupled nonidentical chaotic oscillators. Such a regime is characterized by a Lyapunov spectrum where $N\ensuremath{-}1$ exponents that were zero in the uncoupled regime assume negative values as the coupling strength increases. The dynamics of such collective state is studied, and a comparison is drawn with the case of phase synchronization of a pair of coupled chaotic oscillators. In particular, it is shown that a full phase synchronized state cannot be constructed without at least partial correlation in the chaotic amplitudes.

/pdf/collective-phase-locked-states-in-a-chain-of-coupled-chaotic-3zr71axvja.pdf

Stefano Boccaletti

Papers

Active control of the synchronization manifold in a ring of mutually coupled oscillators

Preprocessing and analyzing genetic data with complex networks: An application to Obstructive Nephropathy

Disorder and decision cost in spatial networks.

Adaptive control of dynamical synchronization on evolving networks with noise disturbances.

Collective phase locked states in a chain of coupled chaotic oscillators