S
Stefano Lai
Researcher at Sant'Anna School of Advanced Studies
Publications - 21
Citations - 535
Stefano Lai is an academic researcher from Sant'Anna School of Advanced Studies. The author has contributed to research in topics: Forelimb & Neurorehabilitation. The author has an hindex of 10, co-authored 20 publications receiving 393 citations. Previous affiliations of Stefano Lai include École Polytechnique Fédérale de Lausanne.
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Journal ArticleDOI
Neuroplastic Changes Following Brain Ischemia and their Contribution to Stroke Recovery: Novel Approaches in Neurorehabilitation
Claudia Alia,Cristina Spalletti,Stefano Lai,Alessandro Panarese,Giuseppe Lamola,Federica Bertolucci,Fabio Vallone,Fabio Vallone,Fabio Vallone,Angelo Di Garbo,Carmelo Chisari,Silvestro Micera,Silvestro Micera,Matteo Caleo +13 more
TL;DR: Advances in the comprehension of post-stroke network reorganization in patients and animal models are discussed, and the potential use of non-invasive brain stimulation techniques to boost recovery is illustrated.
Journal ArticleDOI
Reducing GABA A -mediated inhibition improves forelimb motor function after focal cortical stroke in mice.
Claudia Alia,Cristina Spalletti,Stefano Lai,Alessandro Panarese,Silvestro Micera,Silvestro Micera,Matteo Caleo +6 more
TL;DR: A key role for GABAergic inhibition in functional restoration following ischemia in the adult mouse forelimb motor cortex is reported, demonstrating a key role in limiting motor improvements after cortical stroke.
Journal ArticleDOI
Combining robotic training and inactivation of the healthy hemisphere restores pre-stroke motor patterns in mice.
Cristina Spalletti,Claudia Alia,Stefano Lai,Alessandro Panarese,Sara Conti,Silvestro Micera,Silvestro Micera,Matteo Caleo +7 more
TL;DR: It is demonstrated that the contralesional cortex exerts an enhanced interhemispheric inhibition over the perilesional tissue after focal cortical stroke in mouse forelimb motor cortex, helping recovery in general motor tests and in manual dexterity with remarkable restoration of pre-lesion movement patterns.
Journal ArticleDOI
A Robotic System for Quantitative Assessment and Poststroke Training of Forelimb Retraction in Mice
Cristina Spalletti,Stefano Lai,Marco Mainardi,Alessandro Panarese,A. Ghionzoli,Claudia Alia,Laura Gianfranceschi,Carmelo Chisari,Silvestro Micera,Silvestro Micera,Matteo Caleo +10 more
TL;DR: These results highlight the utility of the devised platform for characterizing post-infarct deficits and improvements of forelimb performance and further research is warranted to widen the understanding of device-dependent rehabilitation effects.
Journal ArticleDOI
Quantitative Kinematic Characterization of Reaching Impairments in Mice After a Stroke
Stefano Lai,Alessandro Panarese,Cristina Spalletti,Claudia Alia,A. Ghionzoli,Matteo Caleo,Silvestro Micera +6 more
TL;DR: The results support the use of kinematic analysis in mice as a tool for both detection of poststroke functional impairments and tracking of motor improvements following rehabilitation.