S
Stephanie R. Fink
Researcher at Mayo Clinic
Publications - 39
Citations - 2402
Stephanie R. Fink is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Fluorescence in situ hybridization & Chronic lymphocytic leukemia. The author has an hindex of 20, co-authored 38 publications receiving 2183 citations.
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Journal ArticleDOI
Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy
Nicholas Erho,Anamaria Crisan,Ismael A. Vergara,Anirban P. Mitra,Mercedeh Ghadessi,Christine Buerki,Eric J. Bergstralh,Thomas M. Kollmeyer,Stephanie R. Fink,Zaid Haddad,Benedikt Zimmermann,Thomas Sierocinski,Karla V. Ballman,Timothy J. Triche,Peter C. Black,R. Jeffrey Karnes,George G. Klee,Elai Davicioni,Robert B. Jenkins +18 more
TL;DR: A genomic classifier was developed and validated in a large patient cohort enriched with prostate cancer metastasis patients and a rising PSA that went on to experience metastatic disease and may be useful for identification of aggressive prostate cancer.
Journal ArticleDOI
Prospective Evaluation of Clonal Evolution During Long-Term Follow-Up of Patients With Untreated Early-Stage Chronic Lymphocytic Leukemia
Tait D. Shanafelt,Thomas E. Witzig,Stephanie R. Fink,Robert B. Jenkins,Sarah F. Paternoster,Stephanie A. Smoley,Kimberly J. Stockero,Danielle M. Nast,Heather C. Flynn,Renee C. Tschumper,Susan Geyer,Clive S. Zent,T. G. Call,Diane F. Jelinek,Neil E. Kay,Gordon W. Dewald +15 more
TL;DR: This clinical trial confirms prospectively that cytogenetic abnormalities detected by FISH can predict overall survival for CLL patients at the time of diagnosis, but also suggests that many patients acquire new abnormalities during the course of their disease.
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The incidence and anatomic site specificity of chromosomal translocations in primary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in North America.
Ellen D. Remstein,Ahmet Dogan,Richard R. Einerson,Sarah F. Paternoster,Stephanie R. Fink,Mark E. Law,Gordon W. Dewald,Paul J. Kurtin +7 more
TL;DR: Differences in incidence and anatomic site specificity of translocations between North American and non-North American cases may reflect geographic variability of infectious or other etiologic factors.
Journal ArticleDOI
Tumorgrafts as In Vivo Surrogates for Women with Ovarian Cancer
S. John Weroha,Marc A. Becker,Sergio Enderica-Gonzalez,Sean C. Harrington,Ann L. Oberg,Matthew J. Maurer,Sarah E. Perkins,Mariam M. AlHilli,Kristina A. Butler,Sarah McKinstry,Stephanie R. Fink,Robert B. Jenkins,Xiaonan Hou,Kimberly R. Kalli,Karin Goodman,Jann N. Sarkaria,Beth Y. Karlan,Amanika Kumar,Scott H. Kaufmann,Lynn C. Hartmann,Paul Haluska +20 more
TL;DR: This is the largest known living tumor bank of patient-derived, ovarian tumorgraft models that can be applied to the development of personalized cancer treatment and response to platinum chemotherapy correlates with the source patient.
Journal ArticleDOI
p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells
Ling Cen,Brett L. Carlson,Mark A. Schroeder,Jamie L. Ostrem,Gaspar J. Kitange,Ann C. Mladek,Stephanie R. Fink,Paul A. Decker,Wenting Wu,Jung-Sik Kim,Todd Waldman,Robert B. Jenkins,Jann N. Sarkaria +12 more
TL;DR: Treatment of GBM6 xenografts with PD0332991 significantly suppressed tumor cell proliferation and prolonged survival and supported the concept that GBM tumors lacking p16(INK4a) expression and with nonamplified CDK4 and wild-type RB status may be more susceptible to Cdk4/6 inhibition using PD033 192991.