Stephen Corcoran

TL;DR: The first high-viscosity injector-based SMX experiments carried out at a US synchrotron source, the Advanced Photon Source (APS), are reported.

TL;DR: In a systematic and direct experimental demonstration of reduced radiation damage in protein crystals with small beams, damage was measured as a function of micron-sized X-ray beams of decreasing dimensions and is less anisotropic than photoelectrons emission probability, consistent with photoelectron trajectory simulations.

TL;DR: An X-ray mini-beam of 8 × 6 µm cross-section was used to collect diffraction data from protein microcrystals with volumes as small as 150–300‵m3 to investigate the benefits of this technique for experiments with small crystals and with large inhomogeneous crystals.

TL;DR: In this paper, the authors describe three major upgrades to their arsenal of tools, "mini-beam" collimators, active beamstop, and an improved goniostat, which has significantly improved the robustness, ease of initial alignment, and reduction of background.

TL;DR: In this article, a 1 −μm beam for challenging micro-diffraction experiments with macromolecular crystals (e.g. small crystals) and for radiation damage studies was developed.