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Stephen D. Silberstein

Researcher at Thomas Jefferson University

Publications -  551
Citations -  44939

Stephen D. Silberstein is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Migraine & Chronic Migraine. The author has an hindex of 100, co-authored 536 publications receiving 39971 citations. Previous affiliations of Stephen D. Silberstein include Thomas Jefferson University Hospital & University of Pennsylvania.

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The International Classification of Headache Disorders, 3rd edition (beta version)

Jes Olesen, +131 more
- 01 Jul 2013 - 
TL;DR: The International Classification of Headache Disorders, 3 edition (beta version), may be reproduced freely for scientific, educational or clinical uses by institutions, societies or individuals as mentioned in this paper. But the authors require the permission of the International Headache Society.
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Practice parameter: Evidence-based guidelines for migraine headache (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology

TL;DR: This practice parameter summarizes the results from the four evidence-based reviews on the management of patients with migraine: specifically, acute, preventive, and nonpharmacologic treatments for migraine, and the role of neuroimaging in patients with headache.
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New Appendix Criteria Open for a Broader Concept of Chronic Migraine

TL;DR: The International Headache Classification Committee has worked out the more inclusive criteria for CM and MOH and it is now recommended that the MOH diagnosis should no longer request improvement after discontinuation of medication overuse but should be given to patients if they have a primary headache plus ongoing medication over use.
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OnabotulinumtoxinA for treatment of chronic migraine: Results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 2 trial

TL;DR: Significant reductions from baseline were observed for onabotulinumtoxinA for headache and migraine days, cumulative hours of headache on headache days and frequency of moderate/severe headache days, which in turn reduced the burden of illness in adults with disabling chronic migraine.
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OnabotulinumtoxinA for Treatment of Chronic Migraine: Pooled Results From the Double-Blind, Randomized, Placebo-Controlled Phases of the PREEMPT Clinical Program

TL;DR: OnabotulinumtoxinA (BOTOX®) as discussed by the authors is an effective prophylactic treatment for chronic migraine in adults with chronic migraines and showed significant improvements compared with placebo in multiple headache symptom measures and significantly reduced headache-related disability and improved functioning, vitality, and overall health-related quality of life.