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Stephen J. Callister

Researcher at Pacific Northwest National Laboratory

Publications -  57
Citations -  2240

Stephen J. Callister is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Proteome & Soil water. The author has an hindex of 24, co-authored 57 publications receiving 1946 citations. Previous affiliations of Stephen J. Callister include Environmental Molecular Sciences Laboratory & Lawrence Berkeley National Laboratory.

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Normalization Approaches for Removing Systematic Biases Associated with Mass Spectrometry and Label-Free Proteomics

TL;DR: Central tendency, linear regression, locally weighted regression, and quantile techniques were investigated for normalization of peptide abundance measurements obtained from high-throughput liquid chromatography-Fourier transform ion cyclotron resonance mass spectrometry (LC-FTICR MS).
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Normalization of peak intensities in bottom-up MS-based proteomics using singular value decomposition

TL;DR: EigenMS is an adaptation of the surrogate variable analysis (SVA) algorithm of Leek and Storey, with the adaptations including a novel approach to preventing overfitting that facilitates the incorporation of EigenMS into an existing proteomics analysis pipeline.
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The future of liquid chromatography-mass spectrometry (LC-MS) in metabolic profiling and metabolomic studies for biomarker discovery

TL;DR: The future utility of liquid chromatography-mass spectrometry (LC-MS) in metabolic profiling and metabolomic studies for biomarker discover will be discussed, with emphasis on recent developments in high-efficiency LC separations, sensitive electrospray ionization approaches, and the benefits to incorporating both in LC-MS-based approaches.