S
Stephen J. Eglen
Researcher at University of Cambridge
Publications - 105
Citations - 2827
Stephen J. Eglen is an academic researcher from University of Cambridge. The author has contributed to research in topics: Retinal waves & Retinal ganglion. The author has an hindex of 28, co-authored 99 publications receiving 2406 citations. Previous affiliations of Stephen J. Eglen include Washington University in St. Louis & University of Sussex.
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Development of retinal ganglion cell structure and function.
TL;DR: The main stages of structural and functional development of retinal ganglion cells (RGCs) are summarized and the development of intrinsic membrane properties and how they might contribute to the spontaneous firing patterns observed before the onset of vision are considered.
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Developmental Loss of Synchronous Spontaneous Activity in the Mouse Retina Is Independent of Visual Experience
TL;DR: It is suggested that visual experience is not required for the loss of synchronous spontaneous activity in the mature retina, and synchronous firing in mice raised in the dark is comparable with that observed in the adult.
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Ten Simple Rules for Taking Advantage of Git and GitHub.
Yasset Perez-Riverol,Laurent Gatto,Rui Wang,Timo Sachsenberg,Julian Uszkoreit,Felipe da Veiga Leprevost,Christian Fufezan,Tobias Ternent,Stephen J. Eglen,Daniel S. Katz,Tom J. Pollard,Alexander Konovalov,Robert M. Flight,Kai Blin,Juan Antonio Vizcaíno +14 more
TL;DR: This study was supported by Wellcome Trust, BBSRC, NSF, EPSRC, and Novo Nordisk Foundation.
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Detecting Pairwise Correlations in Spike Trains: An Objective Comparison of Methods and Application to the Study of Retinal Waves
TL;DR: This work reanalyzes data from seven key studies, which previously used the correlation index to investigate the nature of spontaneous activity, and proposes a novel measure of correlation—the spike time tiling coefficient, which has two undesirable properties: it is unbounded above and confounded by firing rate.
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Following the ontogeny of retinal waves: pan-retinal recordings of population dynamics in the neonatal mouse
Alessandro Maccione,Matthias H. Hennig,Mauro Gandolfo,Oliver Muthmann,James van Coppenhagen,Stephen J. Eglen,Luca Berdondini,Evelyne Sernagor +7 more
TL;DR: Recordings of mouse retinal waves provide a new, deeper understanding of developmental changes in retinal spontaneous activity patterns, which will help researchers in the investigation of the role of early retinal activity during wiring of the visual system.