S
Stephen J. Kennel
Researcher at University of Tennessee Medical Center
Publications - 190
Citations - 7357
Stephen J. Kennel is an academic researcher from University of Tennessee Medical Center. The author has contributed to research in topics: Amyloidosis & Monoclonal antibody. The author has an hindex of 47, co-authored 186 publications receiving 7080 citations. Previous affiliations of Stephen J. Kennel include Oak Ridge National Laboratory & Pacific Northwest National Laboratory.
Papers
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Journal ArticleDOI
Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.
Arnoud Sonnenberg,Jero Calafat,H. Janssen,H Daams,L M van der Raaij-Helmer,R Falcioni,Stephen J. Kennel,John D. Aplin,J Baker,Marilena Loizidou +9 more
TL;DR: Results suggest that different integrin complexes play differing roles in cell-cell and cell- matrix adhesion in the epidermis, and suggest that the cytoplasmic domains of these transmembrane glycoproteins may contribute to the structure of hemidesmosomal plaques.
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High Resolution X-ray Computed Tomography: An Emerging Tool for Small Animal Cancer Research
Michael J. Paulus,Shaun S. Gleason,Stephen J. Kennel,Patricia R. Hunsicker,Dabney K. Johnson +4 more
TL;DR: The development of microCT technology for small animal imaging is reviewed, and key considerations for designing small animal microCT imaging protocols are summarized.
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Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol) s conjugated at their distal terminals to monoclonal antibodies
TL;DR: The approach provides a simple means of conjugating antibodies directly to the distal end of PEG which is already bound to the liposome membrane, and should contribute to the development of superior targetable drug delivery vehicles for use in diagnostics and therapy.
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Lipid composition is important for highly efficient target binding and retention of immunoliposomes.
TL;DR: The results can be understood on the basis of two competing kinetic processes: lung binding whose rate is directly proportional to the antibody content of the immunoliposomes and uptake by RESwhose rate is significantly reduced in the case of the stealth liposomes.
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Comparison of techniques for enzyme immobilization on silicon supports
Aravind Subramanian,Stephen J. Kennel,P. I. Oden,K. Bruce Jacobson,Jonathan Woodward,Mitchel J. Doktycz +5 more
TL;DR: In this paper, the authors evaluated five different methods of enzyme immobilization on silicon substrates, including metal link coupling, entrapment, gelatin, poly-l -lysine adsorption, and pendant amino or epoxide linkers.