S
Stephen M. Roth
Researcher at University of Maryland, College Park
Publications - 133
Citations - 7566
Stephen M. Roth is an academic researcher from University of Maryland, College Park. The author has contributed to research in topics: Skeletal muscle & Strength training. The author has an hindex of 45, co-authored 132 publications receiving 7114 citations. Previous affiliations of Stephen M. Roth include Baylor College of Medicine & Pennington Biomedical Research Center.
Papers
More filters
Journal ArticleDOI
Sex-dependent and independent effects of long-term voluntary wheel running on Bdnf mRNA and protein expression
TL;DR: The findings indicate that the impact of long-term voluntary wheel running on transcriptional and post-translational regulation of Bdnf may be sex-dependent, though the activity-dependent BdnF IV transcript is sensitive to exercise independent of sex.
Journal ArticleDOI
Acute exercise activates p38 MAPK and increases the expression of telomere-protective genes in cardiac muscle.
Andrew T. Ludlow,Andrew T. Ludlow,Laila Gratidão,Laila Gratidão,Lindsay W. Ludlow,Lindsay W. Ludlow,Espen E. Spangenburg,Stephen M. Roth +7 more
TL;DR: In this paper, a positive association between telomere length and exercise training has been shown in cardiac tissue of mice, and the findings are important in understanding how exercise provides a cardioprotective phenotype with ageing.
Journal ArticleDOI
NFKB1 promoter variation implicates shear-induced NOS3 gene expression and endothelial function in prehypertensives and stage I hypertensives.
Joon-Young Park,Iain K. Farrance,Nicola M. Fenty,James M. Hagberg,Stephen M. Roth,David M. Mosser,Min Qi Wang,Han Joong Jo,Toshihiko Okazaki,Steven R. Brant,Michael D. Brown,Michael D. Brown +11 more
TL;DR: It is concluded that the (-94)NFKB1 I/D promoter variation contributes to the modulation of vascular function and adaptability to exercise-induced flow shear stress, most likely due to differences in NFKB1 gene transactivity.
Journal ArticleDOI
Comprehensive fine mapping of chr12q12-14 and follow-up replication identify activin receptor 1B (ACVR1B) as a muscle strength gene
An Windelinckx,Gunther De Mars,Wim Huygens,Maarten Peeters,Barbara Vincent,Cisca Wijmenga,Diether Lambrechts,Christophe Delecluse,Stephen M. Roth,E. Jeffrey Metter,Luigi Ferrucci,Jeroen Aerssens,Robert Vlietinck,Gaston Beunen,Martine Thomis +14 more
TL;DR: The two-staged fine mapping of a previously identified linkage peak for knee strength on chr12q12-14 is described, and genetic variants in the ACVR1B gene account for genetic variation in human muscle strength are identified.
Journal ArticleDOI
Advances in Exercise, Fitness, and Performance Genomics in 2014
Ruth J. F. Loos,James M. Hagberg,Louis Pérusse,Stephen M. Roth,Mark A. Sarzynski,Bernd Wolfarth,Tuomo Rankinen,Claude Bouchard +7 more
TL;DR: New studies continue to support the notion that the genetic susceptibility to obesity, as evidenced by a genomic risk score (GRS), is attenuated by 40%-50% in individuals who are physically active, compared to those who are sedentary.