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Ruth J. F. Loos

Researcher at Icahn School of Medicine at Mount Sinai

Publications -  724
Citations -  108929

Ruth J. F. Loos is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 142, co-authored 647 publications receiving 92485 citations. Previous affiliations of Ruth J. F. Loos include Mount Sinai Hospital & Medical Research Council.

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

TL;DR: A genome-wide search for type 2 diabetes–susceptibility genes identified a common variant in the FTO (fat mass and obesity associated) gene that predisposes to diabetes through an effect on body mass index (BMI).
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Biological, clinical and population relevance of 95 loci for blood lipids

Tanya M. Teslovich, +218 more
- 05 Aug 2010 - 
TL;DR: The results identify several novel loci associated with plasma lipids that are also associated with CAD and provide the foundation to develop a broader biological understanding of lipoprotein metabolism and to identify new therapeutic opportunities for the prevention of CAD.
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Correlates of physical activity: why are some people physically active and others not?

TL;DR: In this article, a broad view of health behaviour causation, with the social and physical environment included as contributors to physical inactivity, particularly those outside the health sector, such as urban planning, transportation systems, and parks and trails, is presented.

Genetic studies of body mass index yield new insights for obesity biology

Adam E. Locke, +481 more
TL;DR: This paper conducted a genome-wide association study and meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals.
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Elizabeth K. Speliotes, +413 more
- 01 Nov 2010 - 
TL;DR: Genetic loci associated with body mass index map near key hypothalamic regulators of energy balance, and one of these loci is near GIPR, an incretin receptor, which may provide new insights into human body weight regulation.