J
Jeroen Aerssens
Researcher at Janssen Pharmaceutica
Publications - 128
Citations - 4781
Jeroen Aerssens is an academic researcher from Janssen Pharmaceutica. The author has contributed to research in topics: Population & Gene. The author has an hindex of 34, co-authored 116 publications receiving 4266 citations. Previous affiliations of Jeroen Aerssens include Maastricht University & Johnson & Johnson Pharmaceutical Research and Development.
Papers
More filters
Journal ArticleDOI
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.
Ilya Chumakov,Marta Blumenfeld,Oxana Guerassimenko,Laurent Cavarec,Marta Palicio,Hadi Abderrahim,Lydie Bougueleret,C Barry,Hiroaki Tanaka,Philippe La Rosa,Anne Puech,Nadia Tahri,Annick Cohen-Akenine,Sylvain Delabrosse,Sébastien Lissarrague,Françoise-Pascaline Picard,Karelle Maurice,Laurent Essioux,Philippe Millasseau,Pascale Grel,Virginie Debailleul,Anne-Marie Simon,Dominique Caterina,Isabelle Dufaure,Kattayoun Malekzadeh,Maria Belova,Jian-Jian Luan,Michel Bouillot,Jean-Luc Sambucy,Gwenael Primas,Martial Saumier,Nadia Boubkiri,Sandrine Martin-Saumier,Myriam Nasroune,Hélène Peixoto,A Delaye,Virginie Pinchot,Mariam Bastucci,Sophie Guillou,Magali Chevillon,Ricardo Sainz-Fuertes,Said Meguenni,Joan Aurich-Costa,Dorra Cherif,Anne Gimalac,Cornelia M. van Duijn,Denis Gauvreau,Gail Ouelette,Isabel Fortier,John Realson,Tatiana Sherbatich,Nadejda Riazanskaia,Evgeny I. Rogaev,Peter Raeymaekers,Jeroen Aerssens,Frank Konings,Walter Luyten,Fabio Macciardi,Pak C. Sham,Richard E. Straub,Daniel R. Weinberger,Nadine Cohen,Daniel Cohen +62 more
TL;DR: A map of 191 single-nucleotide polymorphism (SNPs) was built across a 5-Mb segment from chromosome 13q34 that has been genetically linked to schizophrenia, pointing to the involvement of this N-methyl-d-aspartate receptor regulation pathway in schizophrenia.
Journal ArticleDOI
Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients.
Aimee D C Paulussen,Ronaldus A. H. J. Gilissen,Martin Armstrong,Pieter A. Doevendans,Peter Verhasselt,Hubert J.M. Smeets,Eric Schulze-Bahr,Wilhelm Haverkamp,Giinter Breithardt,Nadine Cohen,Jeroen Aerssens +10 more
TL;DR: It is concluded that missense mutations in the examined cLQ TS genes explain only a minority of aLQTS cases, and are thus unlikely to significantly influence aL QTS susceptibility.
Journal ArticleDOI
Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship.
TL;DR: The inverse relationship OA-OP has been observed and studied for more than 30 years and the proposition that drugs which suppress bone turnover in OP, such as bisphosphonates, may be beneficial for OA is speculative.
Journal ArticleDOI
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis
You-yi Li,Xin Wang,Dianna M. Blau,Mauricio T. Caballero,Daniel R. Feikin,Christopher Hill,Shabir A. Madhi,Saad B. Omer,Eric A. F. Simões,Harry Campbell,Ana Pariente,Darmaa Bardach,Quique Bassat,Jean-Sébastien Casalegno,Giorgi Chakhunashvili,Nigel W Crawford,Daria Danilenko,Lien Anh Ha Do,Marcela Echavarria,Angela Gentile,Aubree Gordon,Terho Heikkinen,Q. Sue Huang,Sophie Jullien,Anand Krishnan,Eduardo López,Joško Markić,Ainara Mira-Iglesias,Hannah C. Moore,Jocelyn Moyes,Lawrence Mwananyanda,D. James Nokes,Faseeha Noordeen,Evangeline Obodai,Nandhini Palani,Candice Romero,Vahid Salimi,Ashish Satav,Eu Jin Seo,Zakhar Shchomak,Rosalyn J. Singleton,Kirill Stolyarov,Sonia K. Stoszek,Anne von Gottberg,Danielle F. Wurzel,Lay-Myint Yoshida,Chee Fu Yung,Heather J. Zar,Harish Nair,Michael E. Abram,Jeroen Aerssens,A. M. Alafaci,Angel Balmaseda,Teresa Bandeira,Ian G. Barr,Ena Batinović,Philippe Beutels,Jinal N. Bhiman,Christopher C Blyth,Louis Bont,Sara S Bressler,Cheryl Cohen,Rachel Cohen,Anna Maria G. Costa,Rowena Crow,Andrew J Daley,Duc Anh Dang,Clarisse Demont,Chris A. Desnoyers,Javier Díez-Domingo,Maduja V M Divarathna,Mignon du Plessis,Madeleine Edgoose,F. Martin Ferolla,Thea Kølsen Fischer,Amanuel Tesfay Gebremedhin,Carlo Giaquinto,Yves Gillet,Roger Hernandez,C Horvat,Etienne Javouhey,Irakli Karseladze,John Kubale,Rakesh Kumar,Bruno Lina,Florencia Lución,Rae Macginty,Federico Martinón-Torres,Alissa McMinn,Adam Meijer,Petra Milić,Adrian Morel,Kim Mulholland,Tuya Mungun,Nickson Murunga,Claire Newbern,Mark P. Nicol,John Kofi Odoom,Peter J. M. Openshaw,Dominique Ploin,Fernando P. Polack,Andrew J. Pollard,Namrata Prasad,Joan Puig-Barberà,Janine Reiche,Noelia Reyes,Bishoy Rizkalla,Shilpa Satao,Ting Shi,Sujatha Sistla,Matthew D. Snape,Yanran Song,Giselle Soto,Forough Tavakoli,Michiko Toizumi,Naranzul Tsedenbal,Maarten van den Berge,Charlotte Vernhes,Claire von Mollendorf,Sibongile Walaza,Gregory J. Walker +120 more
TL;DR: This systematic analysis aims to update RSV-associated acute lower respiratory infection morbidity and mortality at global, regional, and national levels in children aged 0–60 months for 2019, with focus on overall mortality and narrower infant age groups that are targeted by RSV prophylactics in development.
Journal ArticleDOI
High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive Recombination
Steven Sijmons,Kim Thys,Mirabeau Mbong Ngwese,Ellen Van Damme,Jan Dvorak,Marnix Van Loock,Guangdi Li,Ruth Tachezy,Laurent Busson,Jeroen Aerssens,Marc Van Ranst,Piet Maes +11 more
TL;DR: It is shown that cytomegalovirus is significantly more divergent than all other human herpesviruses and highlight hot spots of diversity in the genome, providing the first high-resolution map of human cytomeGalovirus interhost diversity and evolution.