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Steve W. Leung
Researcher at University of Kentucky
Publications - 85
Citations - 1630
Steve W. Leung is an academic researcher from University of Kentucky. The author has contributed to research in topics: Medicine & Myocardial infarction. The author has an hindex of 18, co-authored 73 publications receiving 1220 citations. Previous affiliations of Steve W. Leung include Johns Hopkins University & University of California, Los Angeles.
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Journal ArticleDOI
MultiContrast Delayed Enhancement (MCODE) improves detection of subendocardial myocardial infarction by late gadolinium enhancement cardiovascular magnetic resonance: a clinical validation study
W. Patricia Bandettini,Peter Kellman,Christine Mancini,Christine Mancini,Oscar J Booker,Oscar J Booker,Sujethra Vasu,Steve W. Leung,Joel R. Wilson,Sujata M Shanbhag,Marcus Y. Chen,Andrew E. Arai +11 more
TL;DR: While both PSIR L GE and MCODE were good in identifying MI, MCODE demonstrated more subendocardial MI’s than LGE and identified a larger number of infarcted sectors.
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Cardiac Magnetic Resonance Stress Perfusion Imaging for Evaluation of Patients With Chest Pain
Raymond Y. Kwong,Yin Ge,Kevin Steel,Scott Bingham,Shuaib M Abdullah,Kana Fujikura,Wei Wang,Ankur Pandya,Yi Yun Chen,J. Ronald Mikolich,Sebastian Boland,Andrew E. Arai,W. Patricia Bandettini,Sujata M Shanbhag,Amit R. Patel,Akhil Narang,Afshin Farzaneh-Far,Benjamin Romer,John F. Heitner,Jean Ho,Jaspal Singh,Chetan Shenoy,Andrew Hughes,Steve W. Leung,Meera Marji,Jorge A. Gonzalez,Sandeep Mehta,Dipan J. Shah,Dany Debs,Subha V. Raman,Avirup Guha,Victor A. Ferrari,Jeanette Schulz-Menger,Rory Hachamovitch,Matthias Stuber,Orlando P. Simonetti +35 more
TL;DR: In a multicenter U.S. cohort with stable chest pain syndromes, stress CMR performed at experienced centers offers effective cardiac prognostication.
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Poly(ADP-ribose) polymerase-1 is required for efficient HIV-1 integration
TL;DR: A potential for PARP inhibitors in therapy of HIV type I infection is suggested, as retroviral infection requires integrase-catalyzed DNA strand breaks and protection from infection reflects prevention of viral integration into the host genome.
Journal ArticleDOI
Organic Solutes Rescue the Functional Defect in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator
Xue Mei Zhang,Xi Tao Wang,Hongwen Yue,Steve W. Leung,Patrick H. Thibodeau,Philip Thomas,Sandra E. Guggino +6 more
TL;DR: Treatment of CF bronchial airway cells with these transportable organic solutes restores cAMP-stimulated single channel activity of both CFTR and outwardly rectifying chloride channel in the cell surface membrane and also restores a forskolin- Stimulated macroscopic 36Cl- efflux.
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Simulated 50 % radiation dose reduction in coronary CT angiography using adaptive iterative dose reduction in three- dimensions (AIDR3D)
Marcus Y. Chen,Michael L. Steigner,Steve W. Leung,Kanako K. Kumamaru,Kurt Schultz,Richard T. Mather,Andrew E. Arai,Frank J. Rybicki +7 more
TL;DR: In this paper, the authors compared the image quality of coronary CT angiography (CTA) studies between standard filtered back projection (FBP) and adaptive iterative dose reduction in three-dimensions (AIDR3D) reconstruction using CT noise additional software to simulate reduced radiation exposure.