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Steven N. Goodman
Researcher at Stanford University
Publications - 311
Citations - 38705
Steven N. Goodman is an academic researcher from Stanford University. The author has contributed to research in topics: Cancer & Randomized controlled trial. The author has an hindex of 83, co-authored 279 publications receiving 33971 citations. Previous affiliations of Steven N. Goodman include Johns Hopkins University School of Medicine & Research Triangle Park.
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The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors
Xiaofei Chang,Eugene Izumchenko,Luisa M. Solis,Myoung Sook Kim,Aditi Chatterjee,Shizhang Ling,Constance L. Monitto,Paul M. Harari,Manuel Hidalgo,Steven N. Goodman,Ignacio I. Wistuba,Atul Bedi,David Sidransky +12 more
TL;DR: EGFR activity was markedly decreased during the evolution of resistance to the EGFR tyrosine kinase inhibitor (TKI) erlotinib, with a concomitant increase of mitogen-inducible gene 6 (Mig6), a negative regulator of EGFR through the upregulation of the PI3K-AKT pathway.
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Ethical Considerations in Studying Drug Safety — The Institute of Medicine Report
TL;DR: Three members of the IOM committee discuss the committee's ethics findings and the implications of the report on the ethics and science of FDA-required postmarketing safety research.
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How often do leading biomedical journals use statistical experts to evaluate statistical methods? The results of a survey.
TL;DR: An expanded version of a survey conducted more than 20 years ago with the intention of characterizing contemporary statistical review policies at leading biomedical journals is reported, finding the vast majority of editors regarded statistical review as having substantial incremental value beyond regular peer review and expressed comparatively little concern about the potential increase in reviewing time, cost, and difficulty identifying suitable statistical reviewers.
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Systematic reviews are not biased by results from trials stopped early for benefit
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